Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2143486..2143757 Replicon chromosome
Accession NZ_CP040570
Organism Escherichia coli O157:H7 strain ECP17-1298

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2143616..2143719 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2143486..2143757 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGA23_RS10840 2140041..2140703 - 663 WP_000944243.1 exodeoxyribonuclease X -
FGA23_RS10845 2140727..2141383 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
FGA23_RS10850 2141485..2141715 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FGA23_RS10855 2141854..2142228 + 375 WP_000168751.1 CopC domain-containing protein YobA -
FGA23_RS10860 2142232..2143104 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
FGA23_RS10865 2143117..2143458 + 342 WP_000976483.1 YebY family protein -
- 2143486..2143757 - 272 - - Antitoxin
- 2143616..2143719 + 104 - - Toxin
FGA23_RS10870 2143854..2144510 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
FGA23_RS10875 2144511..2144702 - 192 WP_001296140.1 YebW family protein -
FGA23_RS10880 2144807..2145043 - 237 WP_001295499.1 DUF1480 family protein -
FGA23_RS10885 2145161..2146600 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T126041 NZ_CP040570:2143616-2143719 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT126041 NZ_CP040570:c2143757-2143486 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References