Detailed information of TA system TA126029

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 35396..36021
• Replicon: plasmid pCFSAN059544
• Accession: NZ_CP040565
• Organism: Salmonella enterica subsp. enterica serovar Typhimurium strain SAP17-7699

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: FGA24_RS24200
• Protein ID: WP_000911322.1
• Coordinates: 35396..35794 (-)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: FGA24_RS24205
• Protein ID: WP_000450265.1
• Coordinates: 35794..36021 (-)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FGA24_RS24185	31587..32081	+	495	WP_010999946.1	entry exclusion protein	-
FGA24_RS24190	32117..32848	+	732	WP_000782438.1	complement resistance protein TraT	-
FGA24_RS24195	33225..35387	+	2163	WP_000009318.1	type IV conjugative transfer system coupling protein TraD	-
FGA24_RS24200	35396..35794	-	399	WP_000911322.1	tRNA(fMet)-specific endonuclease VapC	Toxin
FGA24_RS24205	35794..36021	-	228	WP_000450265.1	toxin-antitoxin system antitoxin VapB	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..93869	93869

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-like (40-89)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 19592.50 Da
• Isoelectric Point: 5.5500

>T126029 WP_000911322.1 NZ_CP040565:c35794-35396 [Salmonella enterica subsp. enterica serovar Typhimurium]
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FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 399 bp

>T126029 NZ_CP040565:c35794-35396 [Salmonella enterica subsp. enterica serovar Typhimurium]
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Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 11203.44 Da
• Isoelectric Point: 5.5500

>AT126029 WP_000450265.1 NZ_CP040565:c36021-35794 [Salmonella enterica subsp. enterica serovar Typhimurium]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 228 bp

>AT126029 NZ_CP040565:c36021-35794 [Salmonella enterica subsp. enterica serovar Typhimurium]
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