Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3796579..3797236 Replicon chromosome
Accession NZ_CP040527
Organism Enterobacter ludwigii strain JP9 isolate Tobacco rhizosphere soil

Toxin (Protein)


Gene name cptA Uniprot ID G8LDB6
Locus tag ELJP9_RS17900 Protein ID WP_014171514.1
Coordinates 3796579..3796989 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID G8LDB7
Locus tag ELJP9_RS17905 Protein ID WP_003863437.1
Coordinates 3796970..3797236 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELJP9_RS17880 3792577..3794310 - 1734 WP_014171509.1 single-stranded-DNA-specific exonuclease RecJ -
ELJP9_RS17885 3794316..3795029 - 714 WP_020883731.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
ELJP9_RS17890 3795053..3795949 - 897 WP_014171511.1 site-specific tyrosine recombinase XerD -
ELJP9_RS17895 3796051..3796572 + 522 WP_014171513.1 flavodoxin FldB -
ELJP9_RS17900 3796579..3796989 - 411 WP_014171514.1 protein YgfX Toxin
ELJP9_RS17905 3796970..3797236 - 267 WP_003863437.1 FAD assembly factor SdhE Antitoxin
ELJP9_RS17910 3797531..3798511 + 981 WP_020883730.1 tRNA-modifying protein YgfZ -
ELJP9_RS17915 3798622..3799281 - 660 WP_014171517.1 hemolysin III family protein -
ELJP9_RS17920 3799548..3800279 + 732 WP_086532136.1 MurR/RpiR family transcriptional regulator -
ELJP9_RS17925 3800396..3801829 + 1434 WP_032678925.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16217.15 Da        Isoelectric Point: 11.5020

>T125912 WP_014171514.1 NZ_CP040527:c3796989-3796579 [Enterobacter ludwigii]
VVLWQSDLRVSWRSQWMSLLLHGLVAAFVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRIHARQGEIKLLMDSRLRWQGK
EWEILGMPWMIASGMMLRLRSVDSGRRQHLWLAADSMDSAEWRDLRRMLLQQLTQE

Download         Length: 411 bp

>T125912 NZ_CP040527:c3796989-3796579 [Enterobacter ludwigii]
GTGGTCCTGTGGCAATCTGACCTTCGCGTCTCGTGGCGCTCGCAGTGGATGTCGTTGTTGCTCCACGGCCTGGTCGCGGC
CTTTGTGTTACTGATGCCGTGGCCGCTTAGCTATACGCCTCTGTGGCTGCTGTTGCTGTCGTTTGTGGTGTTTGACAGCG
TGCGCAGCCAGCGCCGCATTCATGCCCGTCAGGGGGAGATCAAATTACTGATGGATTCCCGCCTGCGCTGGCAGGGAAAA
GAGTGGGAAATTCTCGGTATGCCCTGGATGATCGCTTCCGGCATGATGCTGCGGCTACGTAGCGTGGACAGCGGGCGTCG
CCAGCATCTGTGGCTGGCCGCGGACAGTATGGATAGCGCTGAGTGGCGGGACCTGCGTCGGATGTTATTACAGCAGCTGA
CGCAGGAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10526.96 Da        Isoelectric Point: 4.8310

>AT125912 WP_003863437.1 NZ_CP040527:c3797236-3796970 [Enterobacter ludwigii]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
QERGPVAI

Download         Length: 267 bp

>AT125912 NZ_CP040527:c3797236-3796970 [Enterobacter ludwigii]
ATGGATATTAACAACAAGGCCCGTATTCACTGGGCGTGCCGTCGCGGCATGCGTGAACTTGATATTTCCATCATGCCTTT
CTTCGAATATGAGTATGACAGCTTAAGCGATGATGATAAGCGTCTGTTTGTTCGCCTGCTTGAGTCTGACGATCCTGATT
TATTTAACTGGCTGATGAATCACGGCAAACCCGCCGACACCGAGTTGCAACGGATGGTGCAATTAATTCAAACACGGAAT
CAGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A839BUV6

Antitoxin

Source ID Structure
AlphaFold DB A0A837F8P5

References