Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 1379498..1380261 Replicon chromosome
Accession NZ_CP040511
Organism Acidithiobacillus ferrooxidans strain YNTRS-40

Toxin (Protein)


Gene name tacT Uniprot ID B7J9L5
Locus tag FE661_RS07150 Protein ID WP_009565062.1
Coordinates 1379498..1379992 (-) Length 165 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID B7J9L6
Locus tag FE661_RS07155 Protein ID WP_012536505.1
Coordinates 1379989..1380261 (-) Length 91 a.a.

Genomic Context

FE661_RS07115FE661_RS07120FE661_RS07140FE661_RS07175FE661_RS07180FE661_RS07185FE661_RS07130FE661_RS07135FE661_RS07145FE661_RS07150FE661_RS07155FE661_RS07160FE661_RS07165FE661_RS07170
Location: 1375275..1376045 (771 bp)
Type: Others
Protein ID: WP_012536502.1
Location: 1376038..1376880 (843 bp)
Type: Others
Protein ID: WP_012536503.1
Location: 1378717..1378860 (144 bp)
Type: Others
Protein ID: WP_009569579.1
Location: 1382400..1382645 (246 bp)
Type: Others
Protein ID: WP_009568482.1
Location: 1382840..1383976 (1137 bp)
Type: Others
Protein ID: WP_012536507.1
Location: 1384010..1385224 (1215 bp)
Type: Others
Protein ID: WP_012536508.1
Location: 1377598..1378104 (507 bp)
Type: Others
Protein ID: WP_009569577.1
Location: 1378101..1378430 (330 bp)
Type: Others
Protein ID: WP_009569578.1
Location: 1378887..1379153 (267 bp)
Type: Others
Protein ID: WP_012536504.1
Location: 1379498..1379992 (495 bp)
Type: Toxin
Protein ID: WP_009565062.1
Location: 1379989..1380261 (273 bp)
Type: Antitoxin
Protein ID: WP_012536505.1
Location: 1380342..1380554 (213 bp)
Type: Others
Protein ID: WP_009562915.1
Location: 1380722..1380938 (217 bp)
Type: Others
Protein ID: Protein_1407
Location: 1381338..1382159 (822 bp)
Type: Others
Protein ID: WP_012536506.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FE661_RS071151375275..1376045+771WP_012536502.1tRNA 2-thiocytidine(32) synthetase TtcA-
FE661_RS071201376038..1376880+843WP_012536503.1Hsp33 family molecular chaperone HslO-
FE661_RS071301377598..1378104-507WP_009569577.1type II toxin-antitoxin system YhaV family toxin-
FE661_RS071351378101..1378430-330WP_009569578.1type II toxin-antitoxin system PrlF family antitoxin-
FE661_RS071401378717..1378860+144WP_009569579.1hypothetical protein-
FE661_RS071451378887..1379153-267WP_012536504.1type I restriction-modification system subunit M N-terminal domain-containing protein-
FE661_RS071501379498..1379992-495WP_009565062.1GNAT family N-acetyltransferaseToxin
FE661_RS071551379989..1380261-273WP_012536505.1DUF1778 domain-containing proteinAntitoxin
FE661_RS071601380342..1380554-213WP_009562915.1hypothetical protein-
FE661_RS071651380722..1380938-217Protein_1407hypothetical protein-
FE661_RS071701381338..1382159-822WP_012536506.1UDP-2,3-diacylglucosamine diphosphatase-
FE661_RS071751382400..1382645+246WP_009568482.1DUF2934 domain-containing protein-
FE661_RS071801382840..1383976+1137WP_012536507.1glycosyltransferase family 1 protein-
FE661_RS071851384010..1385224+1215WP_012536508.1glycosyltransferase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(29-148)

Antitoxin

Vibrio phage ICP1, Orf50

(4-87)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 18013.83 Da        Isoelectric Point: 10.4415

>T125881 WP_009565062.1 NZ_CP040511:c1379992-1379498 [Acidithiobacillus ferrooxidans]
MSLKLSAPQPLAAVHLLGDFESGEPALDEWLKRRAMNNQLTGASRTFVVVDEENRVRGFYAMAAGAVAHQVATSSVRRNM
PDPVPVMVLGRLAVDSRAQGIKLGAAMLQDAVKRAITVSQNTGVRALLVHALHERAKQFYEHYGFQESPQHPMTLMLRLN
SIKA

Download         Length: 495 bp

>T125881 NZ_CP040511:c1379992-1379498 [Acidithiobacillus ferrooxidans]
ATGAGTTTGAAGCTATCCGCGCCGCAGCCACTTGCGGCCGTGCACCTGTTGGGCGACTTCGAGAGCGGTGAGCCTGCACT
GGATGAGTGGTTAAAACGCCGGGCGATGAACAACCAGCTCACCGGGGCCAGTCGAACCTTTGTGGTCGTTGATGAAGAAA
ATCGGGTGCGCGGCTTCTACGCCATGGCGGCTGGCGCAGTCGCACATCAAGTGGCGACTAGCTCGGTTCGTCGCAATATG
CCCGATCCGGTTCCCGTCATGGTGCTCGGTAGGTTGGCGGTGGATAGTCGAGCGCAAGGCATCAAGCTGGGGGCGGCCAT
GCTGCAGGACGCGGTGAAACGTGCCATCACCGTATCGCAGAACACGGGGGTTCGTGCACTGCTGGTTCATGCGCTCCACG
AACGCGCCAAACAGTTCTATGAGCACTACGGCTTTCAGGAGTCACCACAACATCCGATGACGCTGATGTTGCGCCTGAAT
AGCATCAAGGCTTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10071.52 Da        Isoelectric Point: 5.0914

>AT125881 WP_012536505.1 NZ_CP040511:c1380261-1379989 [Acidithiobacillus ferrooxidans]
MRAAAINLRALPEQRDLIDHAANLLGKNRSDFMLEAACERAQSVLLDQVFFGLDAEKFRQFTAMLDAPPRGNEGLERLMA
VKAPWESNQA

Download         Length: 273 bp

>AT125881 NZ_CP040511:c1380261-1379989 [Acidithiobacillus ferrooxidans]
ATGCGTGCCGCTGCCATCAATTTACGAGCCTTGCCGGAGCAGCGTGATCTCATTGATCACGCCGCCAACCTGTTAGGCAA
AAACCGTTCGGACTTCATGCTGGAAGCCGCCTGCGAGCGTGCGCAATCGGTACTGCTCGATCAGGTGTTTTTTGGGCTGG
ATGCGGAAAAGTTCCGGCAGTTCACCGCCATGCTCGACGCACCGCCTCGTGGCAACGAAGGTCTTGAGCGTCTGATGGCA
GTCAAGGCGCCATGGGAAAGCAATCAAGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBB7J9L5

Antitoxin

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Source
ID
Structure
AlphaFold DBB7J9L6

References