Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4944725..4944970 Replicon chromosome
Accession NZ_CP040443
Organism Escherichia sp. E4742

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4944739..4944842 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4944725..4944970 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FEM44_RS24075 4941844..4943283 + 1440 WP_135522187.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
FEM44_RS24080 4943401..4943637 + 237 WP_002431586.1 DUF1480 family protein -
FEM44_RS24085 4943743..4943934 + 192 WP_135522186.1 YebW family protein -
FEM44_RS24090 4943935..4944591 - 657 WP_135522185.1 protein-serine/threonine phosphatase -
- 4944725..4944970 + 246 - - Antitoxin
- 4944739..4944842 - 104 - - Toxin
FEM44_RS24100 4944999..4945340 - 342 WP_130208467.1 YebY family protein -
FEM44_RS24105 4945354..4946226 - 873 WP_138159223.1 copper homeostasis membrane protein CopD -
FEM44_RS24110 4946230..4946604 - 375 WP_135522184.1 CopC domain-containing protein YobA -
FEM44_RS24115 4946743..4946973 + 231 WP_000916758.1 DNA polymerase III subunit theta -
FEM44_RS24120 4947074..4947730 + 657 WP_135522183.1 carbon-nitrogen hydrolase family protein -
FEM44_RS24125 4947755..4948417 + 663 WP_130208475.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T125822 NZ_CP040443:c4944842-4944739 [Escherichia sp. E4742]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 246 bp

>AT125822 NZ_CP040443:4944725-4944970 [Escherichia sp. E4742]
CTGGCTTAATAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCG
CTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTCCACACG
AAAAGTGGTCAGAAAAAAGCGTCTTTATCATCGTTTTAAAAGTAAAAAAAACGCCCGATCTGATAAAAGATCCTGGGCGT
TTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References