Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 2821995..2822590 Replicon chromosome
Accession NZ_CP040443
Organism Escherichia sp. E4742

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag FEM44_RS13820 Protein ID WP_130237516.1
Coordinates 2822240..2822590 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag FEM44_RS13815 Protein ID WP_135523671.1
Coordinates 2821995..2822246 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FEM44_RS13805 2817660..2821439 + 3780 WP_135523670.1 autotransporter assembly complex protein TamB -
FEM44_RS13810 2821442..2821786 + 345 WP_130206055.1 gamma-glutamylcyclotransferase -
FEM44_RS13815 2821995..2822246 + 252 WP_135523671.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
FEM44_RS13820 2822240..2822590 + 351 WP_130237516.1 endoribonuclease toxin ChpB Toxin
FEM44_RS13830 2822792..2823322 - 531 WP_064525871.1 inorganic diphosphatase -
FEM44_RS13835 2823631..2824587 + 957 WP_064525873.1 galactofuranose ABC transporter substrate-binding protein YtfQ -
FEM44_RS13840 2825134..2826636 + 1503 WP_135385106.1 sugar ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

Antitoxin PemI-like

(1-83)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12580.47 Da        Isoelectric Point: 5.1253

>T125813 WP_130237516.1 NZ_CP040443:2822240-2822590 [Escherichia sp. E4742]
MVKRSEFERGDIVLVGFDPASGHEQQGAGRPALVLSVQAFNQLGMTLVAPITQGGNFARYAGFSVPLHCEEGDVYGVVLV
NQVRMMDLRARQAKRIGLAADEVVEEALLRLQAVVE

Download         Length: 351 bp

>T125813 NZ_CP040443:2822240-2822590 [Escherichia sp. E4742]
ATGGTAAAGCGAAGCGAATTTGAACGGGGAGACATTGTGCTGGTCGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGCCGACCTGCGCTTGTACTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGTTGGTGGCACCCATTACTCAGG
GCGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCGTTACATTGCGAAGAAGGCGATGTGTATGGCGTGGTATTGGTG
AATCAGGTGCGAATGATGGATTTACGCGCCCGCCAGGCAAAGCGTATTGGTCTGGCTGCGGACGAGGTGGTGGAAGAAGC
GTTATTACGTTTGCAGGCGGTGGTGGAATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9339.74 Da        Isoelectric Point: 4.4384

>AT125813 WP_135523671.1 NZ_CP040443:2821995-2822246 [Escherichia sp. E4742]
MRITIKRWGNSAGMIIPNIVMKELNLQPGQSVEAQVSNNQLILTPVLKRYSLEELLAQCDMNAPELSEQDVWGKSTPTGD
EIW

Download         Length: 252 bp

>AT125813 NZ_CP040443:2821995-2822246 [Escherichia sp. E4742]
ATGCGTATTACCATAAAAAGATGGGGGAACAGTGCAGGTATGATCATTCCCAATATCGTAATGAAAGAACTTAACTTACA
GCCGGGGCAGAGCGTGGAGGCGCAGGTGAGCAACAACCAACTGATTTTGACCCCCGTCTTGAAGCGCTACTCGCTTGAAG
AACTGCTGGCGCAATGCGACATGAACGCACCGGAGCTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTACGGGTGAC
GAAATATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References