Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 4969650..4970284 Replicon chromosome
Accession NZ_CP040428
Organism Jejubacter calystegiae strain KSNA2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FEM41_RS23320 Protein ID WP_006687278.1
Coordinates 4969650..4970054 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FEM41_RS23325 Protein ID WP_138098875.1
Coordinates 4970054..4970284 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FEM41_RS23300 4964721..4966046 + 1326 WP_138098872.1 oxalate/formate MFS antiporter -
FEM41_RS24770 4966188..4966349 + 162 WP_206665539.1 hypothetical protein -
FEM41_RS23310 4966450..4968402 - 1953 WP_138098873.1 tetratricopeptide repeat protein -
FEM41_RS23315 4968585..4969475 - 891 WP_138098874.1 oxidoreductase -
FEM41_RS23320 4969650..4970054 - 405 WP_006687278.1 tRNA(fMet)-specific endonuclease VapC Toxin
FEM41_RS23325 4970054..4970284 - 231 WP_138098875.1 antitoxin Antitoxin
FEM41_RS23330 4970425..4970670 + 246 Protein_4556 integrase domain-containing protein -
FEM41_RS23335 4970756..4972333 - 1578 WP_138098876.1 glutamine-hydrolyzing GMP synthase -
FEM41_RS23340 4972399..4973865 - 1467 WP_138099312.1 IMP dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-53)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14977.31 Da        Isoelectric Point: 7.8441

>T125793 WP_006687278.1 NZ_CP040428:c4970054-4969650 [Jejubacter calystegiae]
MLKYMLDTNICIYTIKNKPQAVREAFNQHYGRMCISSVTLMELIYGAEKSASPEKNLRVVEGFIARLEVLNYGIDAAVQT
GQIRAELARAGTPVGPYDSMIAAHARALGLILVTNNTREFERINGLRLEDWSIS

Download         Length: 405 bp

>T125793 NZ_CP040428:c4970054-4969650 [Jejubacter calystegiae]
ATGCTCAAATACATGCTGGATACCAATATCTGTATCTATACGATCAAAAATAAACCTCAGGCAGTCCGGGAGGCGTTTAA
CCAGCATTACGGGCGGATGTGCATCAGTTCTGTCACGCTGATGGAGCTGATTTACGGCGCGGAGAAATCTGCCAGCCCGG
AGAAAAACCTGCGCGTGGTCGAAGGATTCATCGCCCGGTTGGAGGTGCTGAATTATGGTATCGATGCGGCGGTACAGACG
GGGCAAATCCGGGCAGAACTGGCAAGAGCAGGTACGCCCGTTGGCCCGTATGACAGCATGATTGCGGCCCACGCCCGCGC
ACTGGGTTTAATTCTGGTGACGAACAATACCCGTGAGTTCGAACGTATTAATGGATTACGTCTGGAAGACTGGAGTATCA
GCTAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8537.50 Da        Isoelectric Point: 4.5859

>AT125793 WP_138098875.1 NZ_CP040428:c4970284-4970054 [Jejubacter calystegiae]
MEKTTVFKSNRSQAVRLPKAVALPEDVKHVDIVAVGRTRIITPAGESWDSWFDGESVTSDFMAAREQPGDQDREEF

Download         Length: 231 bp

>AT125793 NZ_CP040428:c4970284-4970054 [Jejubacter calystegiae]
ATGGAAAAGACAACCGTATTCAAAAGCAACCGTAGCCAGGCGGTGCGTCTGCCAAAAGCGGTGGCTTTACCGGAGGATGT
CAAACACGTGGATATCGTCGCGGTAGGGCGAACGCGCATTATTACTCCCGCAGGCGAAAGTTGGGACAGCTGGTTTGATG
GTGAGAGCGTGACGTCTGACTTTATGGCCGCCCGTGAACAGCCAGGTGACCAGGACCGGGAAGAGTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References