Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 306463..308161 Replicon chromosome
Accession NZ_CP040428
Organism Jejubacter calystegiae strain KSNA2

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag FEM41_RS01230 Protein ID WP_138093631.1
Coordinates 307232..308161 (+) Length 310 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag FEM41_RS01225 Protein ID WP_196240475.1
Coordinates 306463..307245 (+) Length 261 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FEM41_RS01210 301984..302205 - 222 Protein_237 helix-turn-helix domain-containing protein -
FEM41_RS01215 302202..302663 - 462 WP_138093625.1 hypothetical protein -
FEM41_RS24460 302758..302877 - 120 WP_168198860.1 hypothetical protein -
FEM41_RS01220 302982..306197 - 3216 WP_138093628.1 RNA-directed DNA polymerase -
FEM41_RS01225 306463..307245 + 783 WP_196240475.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
FEM41_RS01230 307232..308161 + 930 WP_138093631.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
FEM41_RS01240 308780..309229 - 450 WP_138093637.1 lipocalin-like domain-containing protein -
FEM41_RS01245 309855..310682 - 828 WP_138093640.1 phosphoenolpyruvate hydrolase family protein -
FEM41_RS01250 310682..311935 - 1254 WP_138093643.1 Tm-1-like ATP-binding domain-containing protein -
FEM41_RS01255 312062..312676 + 615 WP_138093646.1 TetR/AcrR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(13-261)

Antitoxin

Transcriptional regulator AbiEi antitoxin, N-terminal domain

(3-90)


Sequences

Toxin        


Download         Length: 310 a.a.        Molecular weight: 35167.63 Da        Isoelectric Point: 6.9542

>T125775 WP_138093631.1 NZ_CP040428:307232-308161 [Jejubacter calystegiae]
MDLRDIYARQVRLLITALPHVAKESCFALKGGTAINLFVQDFPRLSVDIDLTYKTVTYRDTDLAVINDALMRITESLNGR
PGITAIRQENKADEKRIIVNTADAKIKIEVSPVWRGLLLPPTEMPVCEQVEMEYGFTTMNVVSLADLYGGKICAALDRQH
PRDLFDVLNMLEKPGLTREIFDGFLCYLAGHPRPITELLAPNWDTARIATLYAQEFSGMTQQETSLESLLSVTTLLPQAL
KSHLTDRDRQFLLSYKQNTPDWSLYRYPEIQHLPAIRWKSRNLAVLKDKNPAKYAAAVNKLERVLEQYL

Download         Length: 930 bp

>T125775 NZ_CP040428:307232-308161 [Jejubacter calystegiae]
ATGGATCTGCGTGATATTTATGCCCGACAGGTCAGGCTATTAATTACTGCCCTGCCACATGTGGCGAAGGAGTCCTGTTT
CGCCCTGAAAGGCGGCACGGCAATCAACTTGTTTGTGCAAGATTTCCCTCGCCTGTCGGTGGATATCGATCTGACGTATA
AAACCGTTACTTATCGCGATACCGATCTGGCGGTCATCAATGACGCCTTGATGCGTATTACTGAATCGCTGAACGGCAGA
CCGGGGATCACGGCTATCCGGCAGGAGAATAAAGCGGATGAAAAGCGCATCATCGTTAACACCGCTGACGCGAAGATAAA
GATTGAGGTTAGTCCGGTCTGGCGTGGACTACTATTACCACCAACAGAAATGCCGGTATGTGAACAGGTGGAAATGGAAT
ATGGCTTCACCACCATGAATGTCGTCTCGCTGGCGGATCTTTACGGCGGTAAAATCTGCGCCGCGCTTGACCGCCAGCAT
CCGCGCGATCTGTTTGACGTGCTGAATATGCTGGAAAAGCCGGGCCTGACGCGCGAGATCTTTGACGGTTTTCTTTGCTA
TCTGGCAGGGCATCCCCGCCCCATTACCGAGCTGCTGGCACCAAACTGGGATACAGCGCGGATCGCTACCCTGTACGCAC
AGGAATTTTCAGGCATGACACAGCAGGAAACATCGCTGGAATCCCTTTTATCAGTAACGACTTTGCTGCCACAAGCGCTG
AAATCGCATCTTACGGACAGAGATCGCCAGTTCTTGCTCAGCTATAAGCAAAATACCCCTGACTGGTCGCTGTATCGCTA
TCCTGAAATTCAACACCTACCGGCGATTCGCTGGAAGTCGCGTAACCTGGCGGTGCTGAAGGATAAGAATCCGGCCAAGT
ATGCGGCGGCGGTGAATAAGCTGGAGAGAGTTCTGGAGCAGTACCTTTAG

Antitoxin


Download         Length: 261 a.a.        Molecular weight: 29230.45 Da        Isoelectric Point: 8.1223

>AT125775 WP_196240475.1 NZ_CP040428:306463-307245 [Jejubacter calystegiae]
MPNYLNWLMQNTLPGQVLLQSWLTRNGIDRKLSYLYVQNGWLRRIAHGVYCRTGREPDWVDAIYCLQTQWEKPVRVAGLT
SLALQGHAHYTEPGRQQIWLALPAYVKLPGWFAAFEQSATFVTLYTSGLTVDVTSLTTKLNIDGRQLTGSAPELAAYEIA
CGVPSLISFEHADALFQGMNLLSPRKLQVLLCASHSVKTNRVMLYLARRNEHPYFQYLDQSGIETGSGKRQIVPGGWLEP
DYQITVPRAFKPEGVEDGSA

Download         Length: 783 bp

>AT125775 NZ_CP040428:306463-307245 [Jejubacter calystegiae]
TTGCCAAACTATCTAAACTGGCTGATGCAGAACACCCTCCCCGGTCAGGTGTTGCTCCAGTCATGGCTTACCCGCAACGG
CATAGATCGTAAGCTCTCTTACCTTTATGTCCAGAATGGCTGGCTCAGGCGGATCGCACACGGAGTTTACTGCCGGACGG
GTCGAGAACCAGACTGGGTGGATGCGATTTACTGCCTGCAAACACAGTGGGAAAAACCGGTTCGCGTGGCGGGGCTGACC
AGCCTTGCGCTACAAGGCCATGCCCACTATACCGAACCGGGCAGACAACAGATCTGGCTCGCGCTTCCAGCTTACGTCAA
ACTACCGGGATGGTTCGCCGCCTTTGAACAATCCGCGACGTTCGTCACGCTGTATACGTCGGGCCTCACCGTTGATGTAA
CGTCATTGACTACGAAACTCAATATCGATGGTCGACAGTTAACGGGCAGCGCTCCTGAACTAGCCGCGTATGAGATCGCC
TGCGGCGTTCCTTCGTTGATCTCATTCGAACATGCCGATGCCCTGTTTCAGGGGATGAATCTTCTCAGCCCGCGAAAATT
ACAGGTTTTGCTCTGCGCCAGTCATTCGGTTAAAACCAACCGCGTGATGCTCTACCTTGCCCGACGCAATGAGCATCCTT
ACTTTCAGTACCTCGATCAAAGCGGTATAGAAACCGGCTCGGGAAAACGGCAAATCGTTCCCGGCGGTTGGCTGGAGCCG
GATTATCAAATCACCGTTCCCCGCGCATTTAAACCGGAAGGAGTCGAAGATGGATCTGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References