125774

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 183137..183797 Replicon chromosome
Accession NZ_CP040428
Organism Jejubacter calystegiae strain KSNA2

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag FEM41_RS00750 Protein ID WP_138093378.1
Coordinates 183137..183550 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag FEM41_RS00755 Protein ID WP_138093381.1
Coordinates 183531..183797 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FEM41_RS00730 179050..180783 - 1734 WP_138093366.1 single-stranded-DNA-specific exonuclease RecJ -
FEM41_RS00735 180787..181503 - 717 WP_138093369.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
FEM41_RS00740 181531..182427 - 897 WP_138093372.1 site-specific tyrosine recombinase XerD -
FEM41_RS00745 182577..183098 + 522 WP_138093375.1 flavodoxin FldB -
FEM41_RS00750 183137..183550 - 414 WP_138093378.1 protein YgfX Toxin
FEM41_RS00755 183531..183797 - 267 WP_138093381.1 FAD assembly factor SdhE Antitoxin
FEM41_RS00760 184308..185294 + 987 WP_138093384.1 tRNA-modifying protein YgfZ -
FEM41_RS00765 185325..185978 - 654 WP_138093387.1 hemolysin III family protein -
FEM41_RS00770 186170..186769 + 600 WP_138093390.1 HD domain-containing protein -
FEM41_RS00775 186800..187522 + 723 WP_138099070.1 MurR/RpiR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16188.26 Da        Isoelectric Point: 10.1297

>T125774 WP_138093378.1 NZ_CP040428:c183550-183137 [Jejubacter calystegiae]
VVLWQCDLRVSWQAQWLSLLAHGIVATAILLLPWPLSYMPIWLLLIALVVFDCVRSQRRIHACQGELALLDDDRLRWQGK
VWEFSGRPLPLPGGMLLRLKCPETRKRQLLWLAADCLREEEWRNLRRLLRTRRLQGE

Download         Length: 414 bp

>T125774 NZ_CP040428:c183550-183137 [Jejubacter calystegiae]
GTGGTCCTGTGGCAATGTGATCTCCGGGTCTCCTGGCAGGCGCAGTGGCTCTCTCTGCTGGCGCATGGGATAGTCGCGAC
CGCCATTCTGCTGCTTCCCTGGCCTTTGAGCTATATGCCCATCTGGCTGCTGCTGATTGCCCTTGTGGTATTCGACTGCG
TGCGTAGCCAGCGGCGTATCCATGCCTGTCAGGGAGAGCTGGCGCTGCTCGACGATGACCGTCTGAGGTGGCAGGGTAAG
GTCTGGGAATTTTCTGGCCGACCGTTGCCGCTGCCTGGCGGCATGCTGTTGCGGCTTAAGTGTCCGGAAACCCGCAAGCG
CCAGCTGCTGTGGCTGGCAGCGGATTGTTTGCGGGAAGAGGAGTGGCGCAATCTGCGCCGTCTGTTACGTACCCGTCGGT
TGCAGGGCGAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10486.03 Da        Isoelectric Point: 4.8052

>AT125774 WP_138093381.1 NZ_CP040428:c183797-183531 [Jejubacter calystegiae]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDTLSDTDKQLFVRLLECDDPDLFNWLMNHGAPADAELLRMVRLIQQRN
QERGPVAM

Download         Length: 267 bp

>AT125774 NZ_CP040428:c183797-183531 [Jejubacter calystegiae]
ATGGATATCAATAATAAAGCCCGAATCCACTGGGCTTGCCGTCGTGGCATGCGTGAACTGGATATCTCCATCATGCCCTT
CTTCGAATACGAATACGACACCCTCAGCGATACCGACAAACAGCTGTTCGTCCGTTTGCTGGAGTGTGATGACCCCGACC
TCTTCAACTGGTTGATGAATCACGGTGCGCCCGCGGATGCGGAGTTATTGCGTATGGTACGGTTGATTCAACAGCGGAAC
CAGGAACGTGGTCCTGTGGCAATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References