Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 93004..93539 Replicon chromosome
Accession NZ_CP040428
Organism Jejubacter calystegiae strain KSNA2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FEM41_RS00400 Protein ID WP_138093189.1
Coordinates 93252..93539 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FEM41_RS00395 Protein ID WP_138093186.1
Coordinates 93004..93255 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FEM41_RS00370 89088..89483 - 396 WP_138093171.1 DUF423 domain-containing protein -
FEM41_RS00375 89526..90443 - 918 WP_138093174.1 transcriptional regulator GcvA -
FEM41_RS00380 90854..91081 - 228 WP_138093177.1 YgdI/YgdR family lipoprotein -
FEM41_RS00385 91252..92457 + 1206 WP_138093180.1 cysteine desulfurase CsdA -
FEM41_RS00390 92462..92911 + 450 WP_138093183.1 cysteine desulfurase sulfur acceptor subunit CsdE -
FEM41_RS00395 93004..93255 + 252 WP_138093186.1 antitoxin Antitoxin
FEM41_RS00400 93252..93539 + 288 WP_138093189.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FEM41_RS00405 93666..94475 - 810 WP_138093192.1 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA -
FEM41_RS00410 94571..95671 - 1101 WP_138093195.1 murein transglycosylase A -
FEM41_RS00425 96205..97449 - 1245 WP_138093198.1 N-acetylmuramoyl-L-alanine amidase AmiC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11067.12 Da        Isoelectric Point: 10.4382

>T125773 WP_138093189.1 NZ_CP040428:93252-93539 [Jejubacter calystegiae]
MTYRVKFREDALKEWQKLDKTLQQQFAKKLKKCCENPHIPSAKLHGIKDCYKIKLHASGFRLVYQVMDNKLIIVVVAVGK
RERSGVYNLASERMG

Download         Length: 288 bp

>T125773 NZ_CP040428:93252-93539 [Jejubacter calystegiae]
ATGACTTACAGGGTCAAATTCAGAGAAGACGCACTGAAAGAATGGCAAAAACTGGATAAAACCCTTCAACAGCAGTTTGC
TAAAAAATTGAAGAAGTGCTGTGAAAATCCACATATACCATCTGCAAAACTGCATGGGATTAAAGATTGCTACAAAATAA
AACTTCACGCTTCTGGTTTTCGTCTGGTTTATCAGGTGATGGACAATAAATTAATTATTGTTGTTGTCGCAGTAGGTAAA
CGTGAACGTAGTGGTGTTTACAACCTTGCGAGCGAACGCATGGGGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9181.51 Da        Isoelectric Point: 4.0932

>AT125773 WP_138093186.1 NZ_CP040428:93004-93255 [Jejubacter calystegiae]
MPNIILSDTSASVSELKKNPMATVSAGEGLPVAILNRNQPAFYCVPAELYEKMLDALDDQELVKLVEKRSNQQLLDVDLD
SYL

Download         Length: 252 bp

>AT125773 NZ_CP040428:93004-93255 [Jejubacter calystegiae]
ATGCCTAATATCATTCTGAGCGACACAAGCGCCAGCGTCAGCGAACTCAAAAAAAATCCAATGGCAACAGTGAGTGCCGG
AGAGGGTTTACCGGTCGCAATCCTGAACCGTAACCAGCCTGCATTTTACTGTGTACCGGCAGAGCTGTATGAGAAGATGC
TCGATGCGCTTGATGACCAGGAACTGGTAAAACTGGTAGAAAAACGTAGCAACCAGCAACTACTCGATGTGGATCTGGAT
AGCTACTTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References