Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 4010154..4010711 Replicon chromosome
Accession NZ_CP040392
Organism Kosakonia radicincitans strain DSM 107547

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FEI17_RS19030 Protein ID WP_072438369.1
Coordinates 4010436..4010711 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FEI17_RS19025 Protein ID WP_071920458.1
Coordinates 4010154..4010432 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FEI17_RS19010 4006121..4007116 - 996 WP_007373782.1 ABC transporter permease -
FEI17_RS19015 4007113..4008615 - 1503 WP_149289024.1 sugar ABC transporter ATP-binding protein -
FEI17_RS19020 4008778..4009866 + 1089 WP_144134406.1 oxidoreductase -
FEI17_RS19025 4010154..4010432 + 279 WP_071920458.1 CopG family ribbon-helix-helix protein Antitoxin
FEI17_RS19030 4010436..4010711 + 276 WP_072438369.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FEI17_RS19035 4010786..4011373 - 588 WP_007373776.1 TetR/AcrR family transcriptional regulator -
FEI17_RS19040 4011485..4012228 + 744 WP_007373775.1 SDR family oxidoreductase -
FEI17_RS19045 4012248..4012445 - 198 WP_000460621.1 YbdD/YjiX family protein -
FEI17_RS19050 4012494..4014599 - 2106 WP_035886031.1 carbon starvation protein CstA -
FEI17_RS19055 4014767..4015180 - 414 WP_035886032.1 proofreading thioesterase EntH -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(7-44)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10849.63 Da        Isoelectric Point: 5.1100

>T125721 WP_072438369.1 NZ_CP040392:4010436-4010711 [Kosakonia radicincitans]
MQLEWTRLALQDVERLSKFLFIQNPEAARKVVIMLADAPEMLLLHPQIGPPDESWYPREIRSLFVGSYEMIYELTDSHII
ILRIWHTKEDR

Download         Length: 276 bp

>T125721 NZ_CP040392:4010436-4010711 [Kosakonia radicincitans]
ATGCAGTTAGAATGGACGCGACTCGCTCTTCAGGATGTAGAGAGACTGTCAAAATTCCTGTTTATCCAAAACCCTGAAGC
CGCCCGCAAAGTTGTCATCATGTTGGCTGACGCCCCTGAAATGCTCTTGCTCCACCCACAAATAGGCCCGCCGGATGAAA
GCTGGTATCCGCGCGAAATCCGTTCTTTGTTTGTTGGCAGTTATGAAATGATTTACGAACTGACGGACAGCCATATCATC
ATCCTGCGAATCTGGCATACAAAAGAAGACCGTTAG

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10078.65 Da        Isoelectric Point: 8.6586

>AT125721 WP_071920458.1 NZ_CP040392:4010154-4010432 [Kosakonia radicincitans]
MSGTKVLTAHVPIELADKVDLLAESSERSRGWIIKRALAEYIERAELRQAMIQQGLDAVERGETVSHAEAATWLKSLGTV
NPMPLPGVKKRG

Download         Length: 279 bp

>AT125721 NZ_CP040392:4010154-4010432 [Kosakonia radicincitans]
ATGTCTGGGACGAAAGTACTGACAGCGCATGTACCTATTGAACTCGCCGATAAAGTCGATTTACTTGCCGAAAGCAGCGA
ACGCTCGCGGGGCTGGATTATCAAACGTGCGCTCGCGGAATATATTGAGCGTGCAGAATTACGCCAGGCCATGATCCAGC
AAGGCCTGGATGCCGTTGAACGCGGTGAAACCGTCAGTCATGCAGAAGCGGCGACCTGGCTTAAAAGTCTGGGGACGGTT
AATCCAATGCCGCTGCCAGGCGTTAAAAAACGGGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References