Detailed information of TA system TA125719

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 3665749..3666653
• Replicon: chromosome
• Accession: NZ_CP040392
• Organism: Kosakonia radicincitans strain DSM 107547

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FEI17_RS17375
• Protein ID: WP_035885866.1
• Coordinates: 3666189..3666653 (+)
• Length: 155 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FEI17_RS17370
• Protein ID: WP_007374123.1
• Coordinates: 3665749..3666192 (+)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FEI17_RS17350	3660799..3662565	+	1767	WP_149288957.1	cysteine/glutathione ABC transporter permease/ATP-binding protein CydD	-
FEI17_RS17355	3662566..3664287	+	1722	WP_149288958.1	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	-
FEI17_RS17360	3664393..3665097	+	705	WP_035885865.1	leucyl/phenylalanyl-tRNA--protein transferase	-
FEI17_RS17365	3665382..3665600	+	219	WP_001040187.1	translation initiation factor IF-1	-
FEI17_RS17370	3665749..3666192	+	444	WP_007374123.1	DUF2384 domain-containing protein	Antitoxin
FEI17_RS17375	3666189..3666653	+	465	WP_035885866.1	RES domain-containing protein	Toxin
FEI17_RS17380	3666775..3669063	-	2289	WP_035885867.1	ATP-dependent Clp protease ATP-binding subunit ClpA	-
FEI17_RS17385	3669095..3669415	-	321	WP_007374120.1	ATP-dependent Clp protease adapter ClpS	-
FEI17_RS17390	3669744..3669965	+	222	WP_007374119.1	cold shock-like protein CspD	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-148)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (29-90)

Sequences

Toxin

Protein

• Length: 155 a.a.
• Molecular weight: 17011.33 Da
• Isoelectric Point: 5.9692

>T125719 WP_035885866.1 NZ_CP040392:3666189-3666653 [Kosakonia radicincitans]
VIFYRLVSRRYASEAWTGSGANQYGGRWNHKGHPAVYVASSVSLAALEMLVHVHSDTILSQYGLFSIDIPDKEIEYLDKQ
WLPPDWQENPAPLSTMDLGTAWLEANSAVALVVPSCVIPLENNAILNPQHAGFSKLLKSVKELPFSFDARLASS

Nucleotide

• Length: 465 bp

>T125719 NZ_CP040392:3666189-3666653 [Kosakonia radicincitans]
GTGATTTTTTATCGCCTTGTGTCGCGCCGCTACGCCAGCGAAGCCTGGACCGGCAGCGGTGCGAATCAATATGGCGGCAG
ATGGAATCACAAAGGTCACCCGGCGGTTTATGTTGCCTCATCCGTTTCCCTCGCCGCGCTGGAAATGCTGGTGCATGTAC
ACAGCGACACGATCCTTAGCCAGTACGGCCTGTTCAGTATCGACATTCCCGATAAAGAGATTGAATATCTGGATAAACAG
TGGCTGCCGCCGGACTGGCAGGAAAACCCGGCTCCGCTTTCAACGATGGATCTGGGAACCGCCTGGCTGGAAGCCAATAG
CGCCGTCGCGCTGGTAGTTCCTTCCTGCGTCATTCCTCTGGAAAACAATGCCATCCTCAATCCACAGCACGCTGGATTCA
GCAAGTTACTCAAATCAGTAAAAGAGCTTCCTTTTTCGTTTGATGCGCGTCTGGCTTCATCCTGA

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16407.90 Da
• Isoelectric Point: 9.9132

>AT125719 WP_007374123.1 NZ_CP040392:3665749-3666192 [Kosakonia radicincitans]
MRTWSPEQKPVENALWRFAGFPANRGIKLVQMLNEGLPVSILDNIHEWTEMSRSDILRVTGINERNVARRKSAGRTLTPE
ESERIARLVRVIDAAVQFFGDKKMAYAWLQAPVRGLGNVAPISLIATESGALEVTDLIGRLEHGVFA

Nucleotide

• Length: 444 bp

>AT125719 NZ_CP040392:3665749-3666192 [Kosakonia radicincitans]
ATGAGAACCTGGAGCCCGGAACAAAAACCGGTTGAAAATGCGCTCTGGCGTTTCGCCGGTTTCCCCGCTAACCGCGGTAT
AAAACTTGTTCAGATGTTGAATGAGGGTTTGCCTGTCAGCATTCTGGATAATATCCATGAGTGGACGGAGATGTCCCGCT
CCGACATCCTGCGCGTCACTGGTATTAACGAGCGCAATGTCGCCCGCCGTAAGAGCGCGGGACGCACCTTAACGCCGGAA
GAGAGCGAGCGGATCGCCCGCTTGGTTCGCGTGATCGACGCCGCCGTTCAGTTTTTTGGTGATAAAAAAATGGCGTACGC
CTGGCTACAAGCGCCGGTACGCGGCCTCGGTAACGTTGCTCCTATCTCCCTGATTGCGACTGAAAGTGGCGCACTGGAAG
TCACCGATCTGATTGGCCGCCTGGAGCACGGAGTATTTGCGTGA