Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 914713..915376 Replicon chromosome
Accession NZ_CP040392
Organism Kosakonia radicincitans strain DSM 107547

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag FEI17_RS04470 Protein ID WP_007370254.1
Coordinates 914960..915376 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag FEI17_RS04465 Protein ID WP_007370253.1
Coordinates 914713..914979 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FEI17_RS04445 910156..911589 - 1434 WP_071921388.1 6-phospho-beta-glucosidase BglA -
FEI17_RS04450 911706..912434 - 729 WP_007370250.1 MurR/RpiR family transcriptional regulator -
FEI17_RS04455 912786..913445 + 660 WP_007370251.1 hemolysin III family protein -
FEI17_RS04460 913485..914465 - 981 WP_149288353.1 tRNA-modifying protein YgfZ -
FEI17_RS04465 914713..914979 + 267 WP_007370253.1 FAD assembly factor SdhE Antitoxin
FEI17_RS04470 914960..915376 + 417 WP_007370254.1 protein YgfX Toxin
FEI17_RS04475 915395..915916 - 522 WP_007370255.1 flavodoxin FldB -
FEI17_RS04480 916017..916913 + 897 WP_035889602.1 site-specific tyrosine recombinase XerD -
FEI17_RS04485 916938..917651 + 714 WP_007370257.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
FEI17_RS04490 917657..919390 + 1734 WP_035889603.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16350.31 Da        Isoelectric Point: 10.7373

>T125710 WP_007370254.1 NZ_CP040392:914960-915376 [Kosakonia radicincitans]
VVLWQSELRVSWRAQWISLLLHGLGAALILLMPWPLSYTPLWLLLLSLVVFDCVRSQRRINACHGELKLLMDSRLRWQGM
EWDIIGTPWMLRSGMMLRLRREEDGRRQHLWLAADSMDAQEWRDLRRVISQKPAQGLH

Download         Length: 417 bp

>T125710 NZ_CP040392:914960-915376 [Kosakonia radicincitans]
GTGGTCCTGTGGCAATCTGAGTTACGCGTCTCCTGGCGCGCACAATGGATTTCGCTTTTGCTCCACGGTCTGGGCGCTGC
ACTCATTTTGCTGATGCCCTGGCCTTTGAGTTACACACCGCTGTGGCTGCTGTTGCTGTCGCTGGTGGTTTTTGATTGCG
TGCGCAGCCAGCGGCGGATCAATGCCTGTCATGGCGAACTCAAACTGCTGATGGATTCCCGCCTGCGCTGGCAGGGCATG
GAATGGGATATCATCGGAACGCCGTGGATGTTACGTAGTGGAATGATGCTGCGCTTGCGCCGTGAAGAGGATGGGCGCCG
TCAACATTTATGGCTGGCGGCAGACAGCATGGATGCGCAGGAGTGGCGCGATCTGCGCCGGGTGATATCACAGAAACCGG
CGCAGGGGCTGCATTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10557.98 Da        Isoelectric Point: 5.1069

>AT125710 WP_007370253.1 NZ_CP040392:914713-914979 [Kosakonia radicincitans]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDTLSDDDKQLFVRLLESDDPDLFNWLMNHGKPQDTELQRMVQLIQTRN
RDRGPVAI

Download         Length: 267 bp

>AT125710 NZ_CP040392:914713-914979 [Kosakonia radicincitans]
ATGGATATTAACAACAAAGCCCGTATCCACTGGGCGTGCCGCCGTGGAATGCGTGAACTCGACATCTCAATAATGCCTTT
TTTCGAACATGAGTACGACACGCTGAGCGATGATGACAAACAGCTGTTTGTTCGTCTGCTGGAAAGTGACGATCCTGATT
TATTCAACTGGTTAATGAATCACGGTAAGCCTCAGGACACGGAGTTACAAAGAATGGTGCAGTTAATCCAGACACGGAAT
CGGGATCGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References