Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2024944..2025088 | Replicon | chromosome |
| Accession | NZ_CP040391 | ||
| Organism | Klebsiella pneumoniae strain LSH-KPN25 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2024980..2025082 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2024944..2025088 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FEF28_RS09835 | 2020074..2022134 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| FEF28_RS09840 | 2022138..2022797 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| FEF28_RS09845 | 2022876..2023106 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| FEF28_RS09850 | 2023219..2023593 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| FEF28_RS09855 | 2023597..2024466 | + | 870 | WP_020956678.1 | copper homeostasis membrane protein CopD | - |
| FEF28_RS09860 | 2024483..2024821 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2024944..2025088 | - | 145 | - | - | Antitoxin |
| - | 2024980..2025082 | + | 103 | - | - | Toxin |
| FEF28_RS09865 | 2025215..2025574 | - | 360 | WP_077253379.1 | tyrosine-type recombinase/integrase | - |
| FEF28_RS09870 | 2025573..2026052 | + | 480 | WP_032419797.1 | lysis protein | - |
| FEF28_RS09875 | 2026841..2028346 | + | 1506 | WP_020956680.1 | hypothetical protein | - |
| FEF28_RS09880 | 2028596..2029024 | - | 429 | WP_032419788.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| FEF28_RS09885 | 2029034..2029315 | - | 282 | WP_032419786.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T125695 NZ_CP040391:2024980-2025082 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 145 bp
>AT125695 NZ_CP040391:c2025088-2024944 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
