Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2224405..2224676 Replicon chromosome
Accession NZ_CP040390
Organism Escherichia coli strain A1_136

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2224535..2224638 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2224405..2224676 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FE198_RS10935 2220960..2221622 - 663 WP_000944256.1 exodeoxyribonuclease X -
FE198_RS10940 2221646..2222302 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
FE198_RS10945 2222404..2222634 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FE198_RS10950 2222773..2223147 + 375 WP_000168747.1 CopC domain-containing protein YobA -
FE198_RS10955 2223151..2224023 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
FE198_RS10960 2224036..2224377 + 342 WP_000976472.1 YebY family protein -
- 2224405..2224676 - 272 - - Antitoxin
- 2224535..2224638 + 104 - - Toxin
FE198_RS10965 2224773..2225429 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
FE198_RS10970 2225430..2225621 - 192 WP_001296140.1 YebW family protein -
FE198_RS10975 2225726..2225962 - 237 WP_001295499.1 DUF1480 family protein -
FE198_RS10980 2226080..2227519 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2216272..2240516 24244


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T125664 NZ_CP040390:2224535-2224638 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT125664 NZ_CP040390:c2224676-2224405 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References