Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3642829..3642974 Replicon chromosome
Accession NZ_CP040363
Organism Klebsiella pneumoniae strain R50

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3642865..3642967 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3642829..3642974 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FEM43_RS18105 3637959..3640019 + 2061 WP_004151449.1 oligopeptidase B -
FEM43_RS18110 3640023..3640682 - 660 WP_002911407.1 exodeoxyribonuclease X -
FEM43_RS18115 3640761..3640991 - 231 WP_002911406.1 DNA polymerase III subunit theta -
FEM43_RS18120 3641104..3641478 + 375 WP_004151448.1 CopC domain-containing protein YobA -
FEM43_RS18125 3641482..3642351 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
FEM43_RS18130 3642368..3642706 + 339 WP_185955036.1 YebY family protein -
- 3642829..3642974 - 146 - - Antitoxin
- 3642865..3642967 + 103 - - Toxin
FEM43_RS18140 3643342..3643485 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
FEM43_RS18145 3643590..3644558 - 969 WP_004151446.1 VirK/YbjX family protein -
FEM43_RS18150 3644715..3645368 + 654 WP_019725444.1 protein-serine/threonine phosphatase -
FEM43_RS18155 3645365..3645556 - 192 WP_002911395.1 YebW family protein -
FEM43_RS18160 3645654..3645893 - 240 WP_002911393.1 YebV family protein -
FEM43_RS18165 3646009..3647442 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T125642 NZ_CP040363:3642865-3642967 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT125642 NZ_CP040363:c3642974-3642829 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References