Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1953083..1953228 Replicon chromosome
Accession NZ_CP040354
Organism Klebsiella pneumoniae strain P20

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1953119..1953221 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1953083..1953228 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FEZ11_RS09390 1948213..1950273 + 2061 WP_004151449.1 oligopeptidase B -
FEZ11_RS09395 1950277..1950936 - 660 WP_002911407.1 exodeoxyribonuclease X -
FEZ11_RS09400 1951015..1951245 - 231 WP_002911406.1 DNA polymerase III subunit theta -
FEZ11_RS09405 1951358..1951732 + 375 WP_004151448.1 CopC domain-containing protein YobA -
FEZ11_RS09410 1951736..1952605 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
FEZ11_RS09415 1952622..1952960 + 339 WP_002911404.1 YebY family protein -
- 1953083..1953228 - 146 - - Antitoxin
- 1953119..1953221 + 103 - - Toxin
FEZ11_RS09420 1953596..1953739 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
FEZ11_RS09425 1953844..1954812 - 969 WP_004151446.1 VirK/YbjX family protein -
FEZ11_RS09430 1954969..1955622 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
FEZ11_RS09435 1955619..1955810 - 192 WP_002911395.1 YebW family protein -
FEZ11_RS09440 1955908..1956147 - 240 WP_002911393.1 YebV family protein -
FEZ11_RS09445 1956263..1957696 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T125620 NZ_CP040354:1953119-1953221 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT125620 NZ_CP040354:c1953228-1953083 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References