Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1882855..1883000 Replicon chromosome
Accession NZ_CP040351
Organism Klebsiella pneumoniae strain P39

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1882891..1882993 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1882855..1883000 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FEZ16_RS09065 (FEZ16_09190) 1877985..1880045 + 2061 WP_004151449.1 oligopeptidase B -
FEZ16_RS09070 (FEZ16_09195) 1880049..1880708 - 660 WP_002911407.1 exodeoxyribonuclease X -
FEZ16_RS09075 (FEZ16_09200) 1880787..1881017 - 231 WP_002911406.1 DNA polymerase III subunit theta -
FEZ16_RS09080 (FEZ16_09205) 1881130..1881504 + 375 WP_004151448.1 CopC domain-containing protein YobA -
FEZ16_RS09085 (FEZ16_09210) 1881508..1882377 + 870 WP_048331959.1 copper homeostasis membrane protein CopD -
FEZ16_RS09090 (FEZ16_09215) 1882394..1882732 + 339 WP_016529031.1 YebY family protein -
- 1882855..1883000 - 146 - - Antitoxin
- 1882891..1882993 + 103 - - Toxin
FEZ16_RS09095 1883369..1883512 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
FEZ16_RS09100 (FEZ16_09225) 1883617..1884585 - 969 WP_074185275.1 VirK/YbjX family protein -
FEZ16_RS09105 (FEZ16_09230) 1884742..1885395 + 654 WP_032447686.1 protein-serine/threonine phosphatase -
FEZ16_RS09110 (FEZ16_09235) 1885392..1885583 - 192 WP_002911395.1 YebW family protein -
FEZ16_RS09115 (FEZ16_09240) 1885681..1885920 - 240 WP_002911393.1 YebV family protein -
FEZ16_RS09120 (FEZ16_09245) 1886036..1887469 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T125599 NZ_CP040351:1882891-1882993 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT125599 NZ_CP040351:c1883000-1882855 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References