Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 4319394..4320803 Replicon chromosome
Accession NZ_CP040349
Organism Pseudomonas guguanensis strain HMFL31

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag FE254_RS19910 Protein ID WP_090434041.1
Coordinates 4320234..4320803 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag FE254_RS19905 Protein ID WP_273253345.1
Coordinates 4319394..4320230 (-) Length 279 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FE254_RS19890 (FE254_19960) 4315734..4316639 - 906 WP_273253340.1 GIDE domain-containing protein -
FE254_RS19895 (FE254_19965) 4316641..4317213 - 573 WP_090434048.1 LemA family protein -
FE254_RS19900 (FE254_19970) 4317403..4318737 + 1335 WP_273253343.1 imelysin family protein -
FE254_RS19905 (FE254_19980) 4319394..4320230 - 837 WP_273253345.1 AraC family transcriptional regulator Antitoxin
FE254_RS19910 (FE254_19985) 4320234..4320803 - 570 WP_090434041.1 GNAT family protein Toxin
FE254_RS19915 (FE254_19990) 4320992..4324480 + 3489 WP_273253347.1 PAS domain-containing hybrid sensor histidine kinase/response regulator -
FE254_RS19920 (FE254_19995) 4324694..4325635 + 942 WP_273253350.1 alpha/beta fold hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-146)

Antitoxin

AraC-type arabinose-binding/dimerisation domain

(20-151)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21367.52 Da        Isoelectric Point: 8.9347

>T125575 WP_090434041.1 NZ_CP040349:c4320803-4320234 [Pseudomonas guguanensis]
MFKPQLVTLQRGALRLEPLADADIPALVALAEANRDELLYMSGTQRLDWYRSALAELREQRALPFAVRLGDQLVGTTRFG
DFMNSLPACEIGWTWLDRAQHGSGLNATIKYLMLRHAFDSWGMVRVQLKTAASNLRSQRAIEKLGAVREGLLRNHRRLAD
GRLDDTVLYSITDQEWPALREAMEARFGG

Download         Length: 570 bp

>T125575 NZ_CP040349:c4320803-4320234 [Pseudomonas guguanensis]
ATGTTCAAACCGCAATTGGTCACGCTGCAGCGAGGTGCCCTGCGCCTGGAGCCACTGGCCGATGCCGACATTCCGGCCCT
GGTCGCGCTGGCCGAGGCCAACCGTGACGAGCTGCTGTACATGAGCGGTACCCAGCGTCTGGACTGGTATCGCAGTGCGC
TGGCCGAACTGCGCGAGCAACGCGCGCTGCCGTTCGCGGTTCGCCTCGGCGACCAACTGGTCGGCACCACGCGCTTCGGC
GATTTCATGAACAGCCTGCCGGCCTGCGAGATCGGCTGGACCTGGCTCGATCGCGCCCAGCATGGCAGCGGCCTGAACGC
CACCATCAAGTACCTGATGCTCAGGCATGCCTTCGACAGCTGGGGCATGGTGCGCGTGCAACTGAAAACCGCCGCCAGCA
ACCTGCGCTCGCAACGCGCCATCGAGAAACTCGGCGCCGTGCGTGAGGGCCTGTTGCGTAACCACCGGCGCCTGGCTGAC
GGTCGTCTCGACGACACCGTGCTGTACAGCATCACCGACCAGGAATGGCCGGCGCTGCGCGAGGCGATGGAGGCGCGCTT
CGGCGGCTGA

Antitoxin


Download         Length: 279 a.a.        Molecular weight: 30960.26 Da        Isoelectric Point: 8.2296

>AT125575 WP_273253345.1 NZ_CP040349:c4320230-4319394 [Pseudomonas guguanensis]
MRPLTASERARFSASDDLHGLELLSARFIEHRFAPHVHDGHVIAVLEAGAERYRYRGVDHLAGAGSIALLNPDEVHTGSK
GVEQGWQYRVFYPQPGTFEALLAELELPSASPMFHDSVHHDPLLAARLSALHRLLEDPHSEALHRQTLWREAMLELLQRY
ARLPAPRGVGQESRAVAMAKELLASQLSEPPSLEELAAAVNLSPFHFTRVFRRATGLPPHAWLRQRRLEQARALLRSGCA
AISVAMQLGFADQSHLSRQFKQAYGVSPGEYRAAVARM

Download         Length: 837 bp

>AT125575 NZ_CP040349:c4320230-4319394 [Pseudomonas guguanensis]
ATGCGGCCACTGACGGCAAGCGAACGCGCGCGGTTCAGCGCCAGTGACGATCTGCACGGGCTCGAGCTGCTGTCCGCGCG
CTTCATCGAGCACCGTTTCGCCCCGCACGTGCATGACGGCCATGTGATCGCCGTGCTCGAAGCCGGCGCCGAGCGCTATC
GCTATCGCGGCGTCGACCATCTGGCGGGCGCCGGCAGCATCGCCTTGCTCAATCCGGACGAGGTACACACCGGCTCCAAG
GGGGTCGAGCAGGGCTGGCAGTACCGGGTGTTCTACCCCCAGCCCGGTACATTCGAAGCGCTGCTGGCCGAACTCGAACT
GCCGTCGGCATCGCCGATGTTTCACGACAGCGTGCATCACGACCCGCTGCTGGCGGCGCGCCTGAGCGCGCTGCATCGTC
TGCTTGAGGATCCGCACAGCGAGGCGCTGCACCGCCAGACCCTGTGGCGTGAGGCAATGCTCGAGCTGCTGCAGCGTTAC
GCGCGCCTGCCGGCGCCGCGTGGCGTCGGCCAGGAGTCTCGGGCAGTGGCGATGGCCAAGGAGCTGCTGGCCAGCCAGTT
GAGCGAACCGCCTTCGCTGGAAGAACTGGCGGCGGCGGTCAATCTTTCGCCTTTTCACTTCACCCGGGTGTTCCGTCGAG
CGACAGGGCTGCCGCCGCATGCCTGGCTCAGGCAGCGCCGCCTGGAGCAGGCGCGGGCGCTGCTCAGAAGCGGCTGTGCG
GCCATCAGCGTCGCCATGCAGCTGGGCTTTGCCGACCAGAGCCATCTGTCGCGGCAATTCAAGCAGGCCTATGGCGTCAG
CCCCGGCGAATACCGCGCCGCGGTGGCGCGTATGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References