Detailed information of TA system TA125560

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 22704..23329
• Replicon: plasmid p16-6397.1
• Accession: NZ_CP040322
• Organism: Salmonella enterica subsp. enterica serovar Typhimurium strain PNCS014879

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: E5O16_RS24465
• Protein ID: WP_000911322.1
• Coordinates: 22704..23102 (-)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: E5O16_RS24470
• Protein ID: WP_000450265.1
• Coordinates: 23102..23329 (-)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E5O16_RS24450	18787..19281	+	495	WP_010999946.1	entry exclusion protein	-
E5O16_RS24455	19317..20048	+	732	WP_022743186.1	complement resistance protein TraT	-
E5O16_RS24460	20425..22695	+	2271	WP_023139332.1	type IV conjugative transfer system coupling protein TraD	-
E5O16_RS24465	22704..23102	-	399	WP_000911322.1	tRNA(fMet)-specific endonuclease VapC	Toxin
E5O16_RS24470	23102..23329	-	228	WP_000450265.1	toxin-antitoxin system antitoxin VapB	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..93911	93911

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 19592.50 Da
• Isoelectric Point: 5.5500

>T125560 WP_000911322.1 NZ_CP040322:c23102-22704 [Salmonella enterica subsp. enterica serovar Typhimurium]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 399 bp

>T125560 NZ_CP040322:c23102-22704 [Salmonella enterica subsp. enterica serovar Typhimurium]
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Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 11203.44 Da
• Isoelectric Point: 5.5500

>AT125560 WP_000450265.1 NZ_CP040322:c23329-23102 [Salmonella enterica subsp. enterica serovar Typhimurium]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 228 bp

>AT125560 NZ_CP040322:c23329-23102 [Salmonella enterica subsp. enterica serovar Typhimurium]
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