Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2161280..2161551 Replicon chromosome
Accession NZ_CP040305
Organism Escherichia coli strain HB6

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2161410..2161513 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2161280..2161551 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FEL06_RS10270 2157835..2158497 - 663 WP_000944243.1 exodeoxyribonuclease X -
FEL06_RS10275 2158521..2159177 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
FEL06_RS10280 2159279..2159509 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FEL06_RS10285 2159648..2160022 + 375 WP_000168751.1 CopC domain-containing protein YobA -
FEL06_RS10290 2160026..2160898 + 873 WP_000879315.1 copper homeostasis membrane protein CopD -
FEL06_RS10295 2160911..2161252 + 342 WP_000976483.1 YebY family protein -
- 2161280..2161551 - 272 - - Antitoxin
- 2161410..2161513 + 104 - - Toxin
FEL06_RS10300 2161648..2162304 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
FEL06_RS10305 2162305..2162496 - 192 WP_001296140.1 YebW family protein -
FEL06_RS10310 2162601..2162837 - 237 WP_001295499.1 DUF1480 family protein -
FEL06_RS10315 2162955..2164394 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T125296 NZ_CP040305:2161410-2161513 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT125296 NZ_CP040305:c2161551-2161280 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References