Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/-
Location 302689..303292 Replicon chromosome
Accession NZ_CP040297
Organism Nostoc sp. TCL26-01

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FD725_RS01265 Protein ID WP_179046456.1
Coordinates 302930..303292 (+) Length 121 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FD725_RS01260 Protein ID WP_179046455.1
Coordinates 302689..302940 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FD725_RS01240 298013..298255 - 243 WP_179046452.1 hypothetical protein -
FD725_RS01245 298254..298460 + 207 WP_179046453.1 hypothetical protein -
FD725_RS01250 298520..301123 - 2604 WP_179051377.1 TonB-dependent siderophore receptor -
FD725_RS01255 301291..302277 - 987 WP_179046454.1 AraC family transcriptional regulator -
FD725_RS01260 302689..302940 + 252 WP_179046455.1 hypothetical protein Antitoxin
FD725_RS01265 302930..303292 + 363 WP_179046456.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FD725_RS01270 303668..305257 + 1590 WP_179046457.1 glycosyltransferase family 39 protein -
FD725_RS01275 305353..305718 - 366 WP_179046458.1 hypothetical protein -
FD725_RS01280 306261..308138 + 1878 WP_179046459.1 chloride channel protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(70-146)

Antitoxin

Vibrio phage ICP1, Orf50

(7-81)


Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13897.68 Da        Isoelectric Point: 4.6207

>T125283 WP_179046456.1 NZ_CP040297:302930-303292 [Nostoc sp. TCL26-01]
MQSDNTVSIRFSDEFESELYRLSKRFRKIRSDVQPMIEQLQQGNIVGDRIAGMGEEYIVYKVRVRNSNIQKGKSAGYRLI
YQLESSTSILLLTIYAKSDQEDIDVMEIRDILADFYGDEG

Download         Length: 363 bp

>T125283 NZ_CP040297:302930-303292 [Nostoc sp. TCL26-01]
ATGCAGAGTGATAATACAGTTTCCATTCGATTTTCTGATGAGTTTGAATCCGAACTTTACAGACTATCAAAGAGATTTCG
CAAAATTCGCTCTGATGTTCAACCGATGATCGAACAATTACAACAGGGAAACATTGTTGGCGATCGCATTGCCGGGATGG
GAGAGGAGTATATTGTTTATAAGGTAAGAGTTCGCAACAGTAATATCCAAAAAGGTAAAAGTGCTGGATACAGATTGATT
TATCAACTTGAGTCATCTACAAGTATTTTGCTACTAACGATTTATGCTAAATCAGACCAAGAAGATATTGATGTCATGGA
AATTCGAGATATTTTGGCTGATTTTTATGGTGATGAAGGTTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9189.32 Da        Isoelectric Point: 4.1473

>AT125283 WP_179046455.1 NZ_CP040297:302689-302940 [Nostoc sp. TCL26-01]
MKAIEVTGTIDSQGNLVLDEPIQGTTYPHQVRVIVLVPEPAEEVDPDDTPVEEIKASLRRALQQAKAGQTRPISELWDRI
DAE

Download         Length: 252 bp

>AT125283 NZ_CP040297:302689-302940 [Nostoc sp. TCL26-01]
ATGAAAGCGATTGAAGTTACTGGCACAATTGACTCTCAAGGAAACCTAGTTCTAGATGAACCGATTCAAGGAACAACTTA
TCCTCATCAGGTGCGGGTGATTGTCTTAGTTCCAGAACCAGCAGAAGAGGTTGATCCTGACGATACACCCGTTGAGGAAA
TTAAAGCCAGCTTGAGAAGAGCCTTGCAGCAAGCAAAAGCTGGGCAAACTAGACCAATTAGTGAGCTATGGGACAGAATT
GATGCAGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References