Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 3458465..3459059 Replicon chromosome
Accession NZ_CP040281
Organism Nostoc sp. C057

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FD724_RS14920 Protein ID WP_179073170.1
Coordinates 3458465..3458830 (-) Length 122 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FD724_RS14925 Protein ID WP_179073171.1
Coordinates 3458820..3459059 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FD724_RS14890 3453881..3454252 - 372 WP_179073165.1 hypothetical protein -
FD724_RS14895 3454343..3454579 - 237 WP_179073166.1 hypothetical protein -
FD724_RS14900 3455157..3455441 + 285 WP_179073167.1 DUF427 domain-containing protein -
FD724_RS14905 3455653..3456408 - 756 WP_179073168.1 PEP-CTERM sorting domain-containing protein -
FD724_RS14910 3456564..3457870 - 1307 Protein_2948 hypothetical protein -
FD724_RS14915 3458310..3458477 + 168 WP_179073169.1 hypothetical protein -
FD724_RS14920 3458465..3458830 - 366 WP_179073170.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FD724_RS14925 3458820..3459059 - 240 WP_179073171.1 hypothetical protein Antitoxin
FD724_RS14930 3459636..3462407 - 2772 WP_179075519.1 HEAT repeat domain-containing protein -
FD724_RS14935 3462513..3462959 - 447 WP_179073172.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(34-110)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13898.87 Da        Isoelectric Point: 8.3351

>T125278 WP_179073170.1 NZ_CP040281:c3458830-3458465 [Nostoc sp. C057]
MQSEPPLIQVEATAKFKRNLRILAKKYRNISNDIQPIIEQLQSGELPGDKIPGVGYTIFKLRVKNSDVQKGKSGGYRVIY
YLKTDTNIILVTIYSKSEQEDISAEEIQQILTDFKQQHQEE

Download         Length: 366 bp

>T125278 NZ_CP040281:c3458830-3458465 [Nostoc sp. C057]
ATGCAGAGTGAACCACCTTTGATTCAAGTCGAAGCCACTGCTAAATTTAAACGTAATCTGCGTATCTTAGCCAAAAAGTA
CCGGAATATTAGTAATGATATTCAACCAATAATAGAACAACTGCAATCAGGAGAATTACCAGGAGACAAAATACCCGGAG
TTGGATATACAATTTTTAAGCTACGGGTCAAAAATAGTGATGTTCAAAAAGGTAAAAGTGGTGGGTATCGAGTAATTTAT
TATTTAAAAACAGATACAAATATTATTTTAGTAACCATATACTCAAAATCTGAACAAGAAGACATCTCAGCAGAAGAAAT
TCAACAAATATTAACTGACTTTAAGCAGCAACATCAAGAAGAATAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8743.82 Da        Isoelectric Point: 4.1191

>AT125278 WP_179073171.1 NZ_CP040281:c3459059-3458820 [Nostoc sp. C057]
MKAIEVKGTVNALGQISLDKPLTIAKHSRVRVIVLITEENEEDDELVESAGESFRQGWYDAMTGNTIPVSQLWEGIDAE

Download         Length: 240 bp

>AT125278 NZ_CP040281:c3459059-3458820 [Nostoc sp. C057]
ATGAAAGCAATTGAAGTCAAGGGAACCGTGAACGCATTGGGTCAAATTTCTTTAGACAAGCCGTTGACTATAGCAAAACA
CAGTCGTGTCCGAGTCATTGTTTTAATCACGGAAGAGAATGAAGAGGATGATGAGCTTGTCGAGTCTGCCGGTGAAAGTT
TCCGTCAAGGTTGGTACGATGCGATGACTGGAAATACTATACCTGTATCTCAACTGTGGGAAGGTATTGATGCAGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References