Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 759638..760437 Replicon chromosome
Accession NZ_CP040281
Organism Nostoc sp. C057

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag FD724_RS03170 Protein ID WP_179075393.1
Coordinates 759638..760144 (-) Length 169 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag FD724_RS03175 Protein ID WP_114084565.1
Coordinates 760147..760437 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FD724_RS03160 755302..757677 + 2376 WP_179071556.1 phosphoribosylformylglycinamidine synthase subunit PurL -
FD724_RS03165 757848..759347 + 1500 WP_179071557.1 amidophosphoribosyltransferase -
FD724_RS03170 759638..760144 - 507 WP_179075393.1 GNAT family N-acetyltransferase Toxin
FD724_RS03175 760147..760437 - 291 WP_114084565.1 DUF1778 domain-containing protein Antitoxin
FD724_RS03180 760684..760965 - 282 WP_012407641.1 hypothetical protein -
FD724_RS03185 761031..762077 - 1047 WP_012407642.1 ABC transporter permease -
FD724_RS03190 762144..762662 - 519 WP_179071558.1 adenine phosphoribosyltransferase -
FD724_RS03195 763093..763719 + 627 WP_114084563.1 DUF3038 domain-containing protein -
FD724_RS03200 763716..765146 + 1431 WP_179071559.1 DUF4335 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(45-147)

Antitoxin

Vibrio phage ICP1, Orf50

(12-96)


Sequences

Toxin        


Download         Length: 169 a.a.        Molecular weight: 18787.18 Da        Isoelectric Point: 9.6698

>T125277 WP_179075393.1 NZ_CP040281:c760144-759638 [Nostoc sp. C057]
MKQTKIINPPQPLTLKHDVLEFESKSEALNNWLKEKALKNEGDTARTFVVTIENKVIGYYCLATASVIHLIAVSKAKRNA
PDPIPCMLIGRLAVDIKWEGRGIGSGLLKDAIIRTLTVSQMAGIRCVLVHAKDEEAKRFYLKYGFQPSPIEPLTLMMTLK
DIRANLID

Download         Length: 507 bp

>T125277 NZ_CP040281:c760144-759638 [Nostoc sp. C057]
ATGAAACAAACAAAAATTATTAATCCTCCTCAGCCACTTACTCTTAAGCATGATGTATTAGAATTTGAATCTAAATCAGA
AGCTTTGAATAATTGGCTGAAGGAGAAAGCTTTGAAAAATGAGGGAGATACGGCTAGAACTTTTGTAGTAACTATTGAAA
ATAAAGTAATAGGCTATTACTGTTTAGCAACTGCTTCTGTAATTCATTTAATAGCTGTTAGCAAAGCTAAACGGAACGCA
CCAGACCCTATACCGTGTATGCTTATCGGAAGACTTGCTGTAGACATTAAATGGGAAGGACGGGGTATAGGGTCTGGTTT
ATTAAAAGATGCTATTATTCGTACTTTAACAGTATCCCAAATGGCGGGTATTAGATGTGTTTTGGTTCATGCTAAGGATG
AAGAAGCCAAAAGATTTTATTTAAAATACGGGTTTCAACCCTCGCCAATAGAACCATTAACGCTAATGATGACTTTAAAA
GATATTCGAGCAAACCTTATAGATTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11141.81 Da        Isoelectric Point: 7.7920

>AT125277 WP_114084565.1 NZ_CP040281:c760437-760147 [Nostoc sp. C057]
MLARSKMDNLGRNQVINIRVQEQQRDLIDNAASILGKNRSDFMLEVACREAEKVICNKTFFALDEERYQKFLAILDSPPK
TNEEIRKLLTAKSPWD

Download         Length: 291 bp

>AT125277 NZ_CP040281:c760437-760147 [Nostoc sp. C057]
ATGCTTGCCCGTTCTAAAATGGATAACCTTGGTCGTAACCAAGTAATTAATATTAGAGTTCAAGAACAACAACGGGATTT
AATTGATAATGCTGCATCGATTCTTGGCAAGAACCGTTCTGACTTTATGTTAGAAGTTGCCTGTCGAGAAGCAGAAAAAG
TCATCTGTAACAAGACTTTCTTTGCGTTAGACGAGGAAAGATATCAAAAATTCCTTGCTATTTTGGACTCACCACCTAAA
ACAAATGAAGAAATTCGTAAATTATTAACAGCTAAATCTCCTTGGGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References