Detailed information of TA system TA125271

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 3904156..3904768
• Replicon: chromosome
• Accession: NZ_CP040272
• Organism: Nostoc sp. C052

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: FD723_RS16040
• Protein ID: WP_179066202.1
• Coordinates: 3904403..3904768 (+)
• Length: 122 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: FD723_RS16035
• Protein ID: WP_179066201.1
• Coordinates: 3904156..3904413 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FD723_RS16020	3900146..3901042	+	897	WP_179066198.1	MBL fold metallo-hydrolase	-
FD723_RS16025	3901708..3902772	+	1065	WP_179066199.1	bifunctional riboflavin kinase/FAD synthetase	-
FD723_RS16030	3902911..3903819	+	909	WP_179066200.1	MoxR family ATPase	-
FD723_RS16035	3904156..3904413	+	258	WP_179066201.1	hypothetical protein	Antitoxin
FD723_RS16040	3904403..3904768	+	366	WP_179066202.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
FD723_RS16045	3904956..3905549	+	594	WP_179066203.1	cytochrome C	-
FD723_RS16050	3905863..3908655	+	2793	WP_179066204.1	preprotein translocase subunit SecA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-89)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 122 a.a.
• Molecular weight: 14030.88 Da
• Isoelectric Point: 6.4767

>T125271 WP_179066202.1 NZ_CP040272:3904403-3904768 [Nostoc sp. C052]
MPNEQPSIFIDLTPEYKHNLRDLSKRFRNIRSDVQPIIEQLQQGNFFGNRIAGIGEEYIIYKVRVRNSHIQKGKSVGYRL
IYQVESPTSILLLTIYSKSDREDIGVNEIREILADFDSGES

Nucleotide

• Length: 366 bp

>T125271 NZ_CP040272:3904403-3904768 [Nostoc sp. C052]
ATGCCGAATGAACAGCCATCAATATTCATCGATTTAACTCCTGAATACAAACACAACCTGCGCGACCTTTCAAAGAGATT
TCGCAATATTCGCTCTGATGTTCAACCGATTATCGAGCAATTACAGCAAGGAAATTTTTTCGGCAATCGCATTGCTGGCA
TTGGTGAGGAGTATATTATTTACAAGGTGAGAGTTCGCAACAGTCATATCCAAAAAGGTAAGAGTGTTGGATATCGACTG
ATTTATCAAGTGGAGTCGCCTACAAGTATTTTGCTACTAACGATTTATTCAAAATCTGACCGAGAAGATATTGGTGTAAA
TGAAATCCGAGAAATTTTAGCTGATTTTGACAGTGGGGAAAGTTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9446.63 Da
• Isoelectric Point: 4.1593

>AT125271 WP_179066201.1 NZ_CP040272:3904156-3904413 [Nostoc sp. C052]
MKAIEVTGRIDSQGNLVLDEPIQGNTYPHQVRVIVLVPEQAEAEEIDPDDTPVEEIKASLRRALQQAKAGQRLPLSQMWE
GIDAE

Nucleotide

• Length: 258 bp

>AT125271 NZ_CP040272:3904156-3904413 [Nostoc sp. C052]
ATGAAAGCGATTGAAGTTACTGGCAGGATTGACTCTCAAGGAAACCTAGTTTTAGATGAGCCGATTCAGGGAAACACTTA
TCCTCATCAGGTTCGGGTGATTGTGTTGGTTCCAGAACAAGCAGAAGCAGAAGAGATTGACCCTGATGATACACCCGTTG
AGGAGATTAAAGCTAGCTTGAGGAGAGCCTTGCAGCAAGCAAAAGCTGGTCAACGCCTGCCACTATCTCAAATGTGGGAG
GGAATCGATGCCGAATGA