125222

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2269645..2269916 Replicon chromosome
Accession NZ_CP040263
Organism Escherichia coli strain 631

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2269775..2269878 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2269645..2269916 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EST51_RS11290 2266200..2266862 - 663 WP_000944256.1 exodeoxyribonuclease X -
EST51_RS11295 2266886..2267542 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
EST51_RS11300 2267644..2267874 - 231 WP_000916763.1 DNA polymerase III subunit theta -
EST51_RS11305 2268013..2268387 + 375 WP_000168747.1 CopC domain-containing protein YobA -
EST51_RS11310 2268391..2269263 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
EST51_RS11315 2269276..2269617 + 342 WP_000976472.1 YebY family protein -
- 2269645..2269916 - 272 - - Antitoxin
- 2269775..2269878 + 104 - - Toxin
EST51_RS11320 2270013..2270669 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
EST51_RS11325 2270670..2270861 - 192 WP_001296140.1 YebW family protein -
EST51_RS11330 2270966..2271202 - 237 WP_001295499.1 DUF1480 family protein -
EST51_RS11335 2271320..2272759 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2262335..2285756 23421


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T125222 NZ_CP040263:2269775-2269878 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT125222 NZ_CP040263:c2269916-2269645 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References