125091

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-YafN
Location 107680..108202 Replicon plasmid pRpNDM-1
Accession NZ_CP040184
Organism Raoultella planticola strain Rp_CZ180511

Toxin (Protein)


Gene name stbE Uniprot ID A0A7H0EVH6
Locus tag FDZ05_RS27775 Protein ID WP_014839901.1
Coordinates 107918..108202 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID A0A7H0EVH5
Locus tag FDZ05_RS27770 Protein ID WP_014839900.1
Coordinates 107680..107928 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FDZ05_RS27755 103673..104305 + 633 WP_001567369.1 hypothetical protein -
FDZ05_RS27760 104334..105737 - 1404 WP_001567368.1 ISNCY-like element ISKpn21 family transposase -
FDZ05_RS27765 105849..107381 + 1533 WP_015065592.1 IS3-like element ISKpn38 family transposase -
FDZ05_RS27770 107680..107928 + 249 WP_014839900.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FDZ05_RS27775 107918..108202 + 285 WP_014839901.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FDZ05_RS27780 108393..108869 + 477 WP_117044267.1 hypothetical protein -
FDZ05_RS27785 108875..109552 + 678 WP_042934501.1 hypothetical protein -
FDZ05_RS27790 109569..110288 - 720 WP_042934502.1 cation:proton antiporter -
FDZ05_RS27795 110529..111131 - 603 WP_014839902.1 hypothetical protein -
FDZ05_RS27800 111128..111649 - 522 WP_048336588.1 hypothetical protein -
FDZ05_RS27805 111730..112674 - 945 WP_014839903.1 DsbA family protein -
FDZ05_RS27810 112737..112946 - 210 WP_125316032.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid qnrB4 / blaDHA-1 / sul1 / blaNDM-1 / formA / aac(3)-IId / blaTEM-1B / mph(A) / qacE / ARR-3 / blaTEM-1C / dfrA27 / aadA16 htpB 1..334854 334854


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10866.46 Da        Isoelectric Point: 10.5831

>T125091 WP_014839901.1 NZ_CP040184:107918-108202 [Raoultella planticola]
MTYKLAFNESALKEWKKLGHTIREQFKKKLSERLQNPRVPAAQLHGGKDQYKIKLHGAGYRLVYSVNDEIVTVTVIGVGK
RNNDDIYNATRHRN

Download         Length: 285 bp

>T125091 NZ_CP040184:107918-108202 [Raoultella planticola]
ATGACCTATAAGTTAGCCTTCAATGAATCAGCTTTGAAAGAATGGAAAAAACTGGGTCATACTATTCGGGAGCAATTCAA
AAAGAAGCTTTCCGAACGGCTTCAGAACCCACGGGTGCCCGCAGCACAACTCCATGGAGGTAAAGACCAGTATAAAATAA
AGCTCCATGGCGCGGGTTACCGACTGGTTTACAGTGTCAACGATGAAATTGTGACGGTCACCGTAATTGGGGTGGGCAAA
CGCAACAATGATGATATCTACAACGCAACCCGACACAGAAATTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9071.29 Da        Isoelectric Point: 3.8832

>AT125091 WP_014839900.1 NZ_CP040184:107680-107928 [Raoultella planticola]
MAFQVLTTTAASITELKRDPMGTFNAGEGAPVAILNRNEPAFYCVPPALYAQLMEMLEDQELGRIADERIGEDRIEVNID
DL

Download         Length: 249 bp

>AT125091 NZ_CP040184:107680-107928 [Raoultella planticola]
ATGGCATTTCAGGTTTTAACCACCACAGCAGCCAGCATTACAGAACTTAAACGTGACCCTATGGGTACCTTCAATGCAGG
AGAAGGTGCACCGGTAGCAATCCTGAATCGCAACGAACCCGCTTTTTACTGTGTACCACCAGCCCTGTATGCTCAGCTGA
TGGAAATGCTGGAAGATCAAGAGTTGGGGCGTATTGCTGATGAACGAATCGGTGAGGACCGAATCGAGGTCAACATTGAT
GACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7H0EVH6

Antitoxin

Source ID Structure
AlphaFold DB A0A7H0EVH5

References