Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | Hha-TomB/- |
Location | 4436551..4437170 | Replicon | chromosome |
Accession | NZ_CP040183 | ||
Organism | Raoultella planticola strain Rp_CZ180511 |
Toxin (Protein)
Gene name | Hha | Uniprot ID | A0A514EV16 |
Locus tag | FDZ05_RS21080 | Protein ID | WP_004858783.1 |
Coordinates | 4436952..4437170 (+) | Length | 73 a.a. |
Antitoxin (Protein)
Gene name | TomB | Uniprot ID | A0A514EV88 |
Locus tag | FDZ05_RS21075 | Protein ID | WP_004858785.1 |
Coordinates | 4436551..4436925 (+) | Length | 125 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FDZ05_RS21065 | 4431662..4432855 | + | 1194 | WP_032689203.1 | multidrug efflux RND transporter periplasmic adaptor subunit AcrA | - |
FDZ05_RS21070 | 4432878..4436024 | + | 3147 | WP_032689204.1 | multidrug efflux RND transporter permease subunit | - |
FDZ05_RS21075 | 4436551..4436925 | + | 375 | WP_004858785.1 | Hha toxicity modulator TomB | Antitoxin |
FDZ05_RS21080 | 4436952..4437170 | + | 219 | WP_004858783.1 | hemolysin expression modulator Hha | Toxin |
FDZ05_RS21085 | 4437322..4437888 | + | 567 | WP_032689205.1 | maltose O-acetyltransferase | - |
FDZ05_RS21090 | 4437988..4438458 | + | 471 | WP_004858780.1 | YlaC family protein | - |
FDZ05_RS21095 | 4438433..4439884 | - | 1452 | WP_180888691.1 | PLP-dependent aminotransferase family protein | - |
FDZ05_RS21100 | 4439986..4440696 | + | 711 | WP_032689207.1 | GNAT family N-acetyltransferase | - |
FDZ05_RS21105 | 4440693..4440833 | - | 141 | WP_003859006.1 | type B 50S ribosomal protein L36 | - |
FDZ05_RS21110 | 4440836..4441096 | - | 261 | WP_032689208.1 | type B 50S ribosomal protein L31 | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 73 a.a. Molecular weight: 8570.90 Da Isoelectric Point: 7.9907
>T125089 WP_004858783.1 NZ_CP040183:4436952-4437170 [Raoultella planticola]
MSGEPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFYSAADHRLAELTMNKLYDKIPTSVWKFIR
MSGEPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFYSAADHRLAELTMNKLYDKIPTSVWKFIR
Download Length: 219 bp
>T125089 NZ_CP040183:4436952-4437170 [Raoultella planticola]
ATGTCTGGTGAACCATTAACCAAAACAGACTATTTGATGCGCTTACGTCGCTGTCAGACAATTGATACGCTGGAACGCGT
AATTGAAAAAAACAAATATGAACTTTCAGATAACGAACTGGCTGTATTTTACTCAGCGGCCGATCACCGTCTTGCTGAAT
TGACCATGAATAAACTCTACGACAAAATCCCGACATCGGTGTGGAAGTTCATTCGCTAA
ATGTCTGGTGAACCATTAACCAAAACAGACTATTTGATGCGCTTACGTCGCTGTCAGACAATTGATACGCTGGAACGCGT
AATTGAAAAAAACAAATATGAACTTTCAGATAACGAACTGGCTGTATTTTACTCAGCGGCCGATCACCGTCTTGCTGAAT
TGACCATGAATAAACTCTACGACAAAATCCCGACATCGGTGTGGAAGTTCATTCGCTAA
Antitoxin
Download Length: 125 a.a. Molecular weight: 14411.19 Da Isoelectric Point: 4.8989
>AT125089 WP_004858785.1 NZ_CP040183:4436551-4436925 [Raoultella planticola]
MDEYSPKRHDIAQLRFLCETLYHDCLANLEESNHGWVNDPTSAINLQLNELIEHIATFALNYKIKYAEDNKLIAQLDEYL
DDTFMLFSSYGINTADLQKWRKSGNRLFRCFVNASRENPASLSC
MDEYSPKRHDIAQLRFLCETLYHDCLANLEESNHGWVNDPTSAINLQLNELIEHIATFALNYKIKYAEDNKLIAQLDEYL
DDTFMLFSSYGINTADLQKWRKSGNRLFRCFVNASRENPASLSC
Download Length: 375 bp
>AT125089 NZ_CP040183:4436551-4436925 [Raoultella planticola]
ATGGACGAATACTCGCCAAAAAGACATGATATCGCGCAGCTTCGATTTCTTTGCGAAACCCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGTAACCACGGGTGGGTGAATGACCCGACGTCGGCTATCAATCTTCAACTTAATGAATTGATCGAAC
ACATAGCCACGTTCGCGCTTAATTATAAAATTAAGTATGCTGAGGATAATAAACTGATCGCTCAGCTGGACGAATACCTG
GATGACACTTTTATGTTGTTCAGCAGTTATGGCATTAACACGGCCGATCTACAGAAATGGCGCAAATCGGGAAATCGGTT
ATTCCGATGTTTTGTCAACGCCAGCCGGGAAAATCCGGCAAGTCTTTCTTGTTAG
ATGGACGAATACTCGCCAAAAAGACATGATATCGCGCAGCTTCGATTTCTTTGCGAAACCCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGTAACCACGGGTGGGTGAATGACCCGACGTCGGCTATCAATCTTCAACTTAATGAATTGATCGAAC
ACATAGCCACGTTCGCGCTTAATTATAAAATTAAGTATGCTGAGGATAATAAACTGATCGCTCAGCTGGACGAATACCTG
GATGACACTTTTATGTTGTTCAGCAGTTATGGCATTAACACGGCCGATCTACAGAAATGGCGCAAATCGGGAAATCGGTT
ATTCCGATGTTTTGTCAACGCCAGCCGGGAAAATCCGGCAAGTCTTTCTTGTTAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A514EV16 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A514EV88 |