Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 958758..959415 Replicon chromosome
Accession NZ_CP040183
Organism Raoultella planticola strain Rp_CZ180511

Toxin (Protein)


Gene name cptA Uniprot ID A0A2X2EG10
Locus tag FDZ05_RS04720 Protein ID WP_032690815.1
Coordinates 959005..959415 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A514ELX1
Locus tag FDZ05_RS04715 Protein ID WP_004867358.1
Coordinates 958758..959024 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FDZ05_RS04690 953905..955338 - 1434 WP_032690812.1 6-phospho-beta-glucosidase -
FDZ05_RS04695 955458..956186 - 729 WP_032690813.1 MurR/RpiR family transcriptional regulator -
FDZ05_RS04700 956236..956547 + 312 WP_004867365.1 N(4)-acetylcytidine aminohydrolase -
FDZ05_RS04705 956709..957368 + 660 WP_004867362.1 hemolysin III family protein -
FDZ05_RS04710 957478..958461 - 984 WP_032690814.1 tRNA-modifying protein YgfZ -
FDZ05_RS04715 958758..959024 + 267 WP_004867358.1 FAD assembly factor SdhE Antitoxin
FDZ05_RS04720 959005..959415 + 411 WP_032690815.1 protein YgfX Toxin
FDZ05_RS04725 959421..959942 - 522 WP_032690816.1 flavodoxin FldB -
FDZ05_RS04730 960121..961017 + 897 WP_180888876.1 site-specific tyrosine recombinase XerD -
FDZ05_RS04735 961040..961753 + 714 WP_032690818.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
FDZ05_RS04740 961759..963492 + 1734 WP_032696678.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16198.10 Da        Isoelectric Point: 11.3349

>T125078 WP_032690815.1 NZ_CP040183:959005-959415 [Raoultella planticola]
VVLWQSDLRISWRSQWFSLLLHGIVAAIVLLMPWPLSYTPLWLLLLSLVVFDSVRSQRRIHACRGEIKLMTDSRLRWQKA
EWEIVGTPWVINSGMLLRLQDMQTRRRQHLWVAADSMDAKEWRDLRRLVLQKPAQD

Download         Length: 411 bp

>T125078 NZ_CP040183:959005-959415 [Raoultella planticola]
GTGGTCCTGTGGCAATCTGATTTACGCATTTCCTGGCGCTCGCAGTGGTTCTCGCTGCTGCTGCACGGCATTGTGGCGGC
TATTGTCTTGCTGATGCCCTGGCCGCTGAGCTACACACCGCTATGGCTATTGCTGCTGTCGCTGGTGGTGTTCGACAGCG
TGCGCAGCCAGCGGCGGATCCACGCCTGCCGGGGTGAAATAAAGCTGATGACCGATTCGCGTTTGCGTTGGCAAAAAGCG
GAATGGGAGATTGTCGGCACGCCGTGGGTGATTAATAGCGGGATGTTGCTGCGCCTGCAGGATATGCAAACGCGTCGCCG
CCAGCATCTGTGGGTCGCTGCAGACAGTATGGACGCCAAAGAGTGGCGAGATCTGCGCCGGTTGGTTTTACAAAAACCGG
CACAGGATTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10553.05 Da        Isoelectric Point: 4.8432

>AT125078 WP_004867358.1 NZ_CP040183:958758-959024 [Raoultella planticola]
MDITNKARIHWACRRGMRELDISIMPFFEYEYDTLSDEDKQLFIRLLENDDPDLFNWLMNHGEPADAQLQRMVKLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT125078 NZ_CP040183:958758-959024 [Raoultella planticola]
ATGGACATTACGAATAAAGCCCGCATCCACTGGGCATGCCGCAGGGGTATGCGTGAACTTGATATCTCCATCATGCCGTT
TTTCGAGTATGAGTACGATACGCTCAGCGATGAAGACAAACAGCTGTTTATCCGTCTGTTAGAAAACGACGATCCGGACC
TGTTTAACTGGCTGATGAATCATGGCGAACCGGCTGATGCACAACTGCAACGGATGGTAAAATTAATCCAGACTCGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2X2EG10

Antitoxin

Source ID Structure
AlphaFold DB A0A514ELX1

References