Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1854660..1855417 Replicon chromosome
Accession NZ_CP040182
Organism Serratia fonticola strain MS5

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag FD644_RS08430 Protein ID WP_081367093.1
Coordinates 1854660..1855142 (-) Length 161 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID A0A448SFY1
Locus tag FD644_RS08435 Protein ID WP_071683113.1
Coordinates 1855133..1855417 (-) Length 95 a.a.

Genomic Context

FD644_RS08405FD644_RS08410FD644_RS08415FD644_RS08420FD644_RS08425FD644_RS08445FD644_RS08450FD644_RS08455FD644_RS08430FD644_RS08435FD644_RS08440
Location: 1850580..1851317 (738 bp)
Type: Others
Protein ID: WP_059200166.1
Location: 1851384..1852115 (732 bp)
Type: Others
Protein ID: WP_021805279.1
Location: 1852112..1853119 (1008 bp)
Type: Others
Protein ID: WP_071683109.1
Location: 1853128..1853772 (645 bp)
Type: Others
Protein ID: WP_021805277.1
Location: 1853845..1854636 (792 bp)
Type: Others
Protein ID: WP_071683111.1
Location: 1857675..1858064 (390 bp)
Type: Others
Protein ID: WP_024483149.1
Location: 1858058..1858405 (348 bp)
Type: Others
Protein ID: WP_021805273.1
Location: 1858406..1860172 (1767 bp)
Type: Others
Protein ID: WP_059200169.1
Location: 1854660..1855142 (483 bp)
Type: Toxin
Protein ID: WP_081367093.1
Location: 1855133..1855417 (285 bp)
Type: Antitoxin
Protein ID: WP_071683113.1
Location: 1855739..1857028 (1290 bp)
Type: Others
Protein ID: WP_021805275.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FD644_RS084051850580..1851317+738WP_059200166.15-oxoprolinase subunit PxpA-
FD644_RS084101851384..1852115+732WP_021805279.1DUF969 domain-containing protein-
FD644_RS084151852112..1853119+1008WP_071683109.1DUF979 domain-containing protein-
FD644_RS084201853128..1853772+645WP_021805277.1pyroglutamyl-peptidase I-
FD644_RS084251853845..1854636+792WP_071683111.1endonuclease VIII-
FD644_RS084301854660..1855142-483WP_081367093.1GNAT family N-acetyltransferaseToxin
FD644_RS084351855133..1855417-285WP_071683113.1DUF1778 domain-containing proteinAntitoxin
FD644_RS084401855739..1857028-1290WP_021805275.1citrate synthase-
FD644_RS084451857675..1858064+390WP_024483149.1succinate dehydrogenase cytochrome b556 subunit-
FD644_RS084501858058..1858405+348WP_021805273.1succinate dehydrogenase membrane anchor subunit-
FD644_RS084551858406..1860172+1767WP_059200169.1succinate dehydrogenase flavoprotein subunit-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(25-148)

Antitoxin

Vibrio phage ICP1, Orf50

(5-93)


Sequences

Toxin        


Download         Length: 161 a.a.        Molecular weight: 18015.91 Da        Isoelectric Point: 7.7995

>T125062 WP_081367093.1 NZ_CP040182:c1855142-1854660 [Serratia fonticola]
MEIIIIAPELLTEEHILQPFDCGNEVLSDWLRRRAMRNQLLNASRTFVICLEGTKRVVGYYSIATGSVSHADLGRSLRQN
MPDPVPIVLLGRLAVDVCTQGHRFGKWLLNDAVRRVANLADQVGIKAIMVHAIDDQARAFYEYFGFVQSPIAANTLFYKI

Download         Length: 483 bp

>T125062 NZ_CP040182:c1855142-1854660 [Serratia fonticola]
ATGGAAATAATCATTATCGCGCCGGAACTGCTGACAGAAGAGCATATTCTCCAACCATTCGACTGCGGAAATGAGGTGTT
GAGCGACTGGTTACGCCGTCGAGCCATGAGAAACCAACTCCTGAATGCCTCCCGCACTTTCGTTATTTGTCTGGAAGGCA
CCAAGCGTGTTGTGGGTTATTACTCCATTGCAACCGGTTCCGTCAGTCACGCCGATTTAGGCCGTAGCCTTCGCCAAAAC
ATGCCAGATCCTGTTCCCATCGTCCTGCTGGGACGTCTGGCCGTTGATGTATGTACCCAAGGGCATCGCTTTGGCAAGTG
GCTGCTTAATGATGCTGTAAGGCGTGTTGCCAATCTGGCAGACCAAGTGGGTATTAAAGCCATCATGGTGCACGCGATAG
ATGATCAAGCGAGAGCATTCTATGAGTACTTCGGCTTCGTCCAGTCTCCCATCGCTGCAAACACACTCTTCTACAAGATT
TGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11066.66 Da        Isoelectric Point: 8.5275

>AT125062 WP_071683113.1 NZ_CP040182:c1855417-1855133 [Serratia fonticola]
MQKTVRKPTRDKQINVRATEEERAVIDYAASLVNKNRTDFIIEKAVHEAQNIILDQRVFVLDDARYQAFIEQLEAPVQNV
EGRKRLMDVKPEWK

Download         Length: 285 bp

>AT125062 NZ_CP040182:c1855417-1855133 [Serratia fonticola]
ATGCAGAAAACCGTTCGTAAACCGACTCGTGACAAACAGATTAACGTCCGGGCGACCGAAGAAGAGCGTGCAGTCATCGA
CTATGCTGCGAGTCTGGTCAATAAGAACCGGACCGACTTCATCATTGAGAAGGCGGTTCATGAAGCACAGAACATCATCC
TGGATCAGCGGGTATTCGTGCTTGATGATGCACGCTATCAGGCATTCATTGAACAGCTTGAAGCTCCTGTGCAAAACGTC
GAAGGGCGCAAGCGCTTAATGGATGTGAAGCCTGAATGGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A448SFY1

References