Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 807380..807951 Replicon chromosome
Accession NZ_CP040182
Organism Serratia fonticola strain MS5

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FD644_RS03710 Protein ID WP_071681261.1
Coordinates 807676..807951 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID U2NJB3
Locus tag FD644_RS03705 Protein ID WP_021179086.1
Coordinates 807380..807667 (+) Length 96 a.a.

Genomic Context

FD644_RS03705FD644_RS03710FD644_RS03730FD644_RS03675FD644_RS03680FD644_RS03685FD644_RS03690FD644_RS03695FD644_RS03700FD644_RS03715FD644_RS03720FD644_RS03725
Location: 807380..807667 (288 bp)
Type: Antitoxin
Protein ID: WP_021179086.1
Location: 807676..807951 (276 bp)
Type: Toxin
Protein ID: WP_071681261.1
Location: 812244..812768 (525 bp)
Type: Others
Protein ID: WP_071681265.1
Location: 802616..803404 (789 bp)
Type: Others
Protein ID: WP_024483394.1
Location: 803404..804255 (852 bp)
Type: Others
Protein ID: WP_071681259.1
Location: 804248..805333 (1086 bp)
Type: Others
Protein ID: WP_021807490.1
Location: 805333..805914 (582 bp)
Type: Others
Protein ID: WP_059199560.1
Location: 805918..806361 (444 bp)
Type: Others
Protein ID: WP_071681260.1
Location: 806362..807090 (729 bp)
Type: Others
Protein ID: WP_021807487.1
Location: 807948..808412 (465 bp)
Type: Others
Protein ID: WP_071681262.1
Location: 808802..810940 (2139 bp)
Type: Others
Protein ID: WP_071681263.1
Location: 811252..812139 (888 bp)
Type: Others
Protein ID: WP_071681264.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FD644_RS03675802616..803404-789WP_024483394.1phosphonate C-P lyase system protein PhnK-
FD644_RS03680803404..804255-852WP_071681259.1alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase PhnJ-
FD644_RS03685804248..805333-1086WP_021807490.1carbon-phosphorus lyase complex subunit PhnI-
FD644_RS03690805333..805914-582WP_059199560.1phosphonate C-P lyase system protein PhnH-
FD644_RS03695805918..806361-444WP_071681260.1phosphonate C-P lyase system protein PhnG-
FD644_RS03700806362..807090-729WP_021807487.1phosphonate metabolism transcriptional regulator PhnF-
FD644_RS03705807380..807667+288WP_021179086.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
FD644_RS03710807676..807951+276WP_071681261.1type II toxin-antitoxin system RelE/ParE family toxinToxin
FD644_RS03715807948..808412-465WP_071681262.1anaerobic ribonucleoside-triphosphate reductase-activating protein-
FD644_RS03720808802..810940-2139WP_071681263.1anaerobic ribonucleoside-triphosphate reductase-
FD644_RS03725811252..812139-888WP_071681264.1LysR family transcriptional regulator-
FD644_RS03730812244..812768+525WP_071681265.1NAD(P)H-dependent oxidoreductase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-44)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10628.30 Da        Isoelectric Point: 4.2503

>T125057 WP_071681261.1 NZ_CP040182:807676-807951 [Serratia fonticola]
MRIEWDDVALQDRERIFEFLYPLTPLAAEQVDDEIELAVESLLENPEMGRPWYGEARKLVISKASLLMIYVILDEVIKVL
AVAHQREKFPN

Download         Length: 276 bp

>T125057 NZ_CP040182:807676-807951 [Serratia fonticola]
ATGCGCATCGAATGGGACGACGTTGCGTTGCAAGATCGGGAACGCATTTTTGAATTTCTTTATCCACTCACTCCATTGGC
CGCGGAACAAGTTGATGATGAGATTGAACTTGCCGTTGAGTCGCTGCTAGAAAACCCAGAAATGGGCAGGCCTTGGTATG
GGGAAGCTCGCAAACTGGTGATCAGTAAAGCCTCCCTATTGATGATTTATGTCATTTTGGATGAGGTGATAAAGGTTTTA
GCCGTCGCCCATCAGCGTGAAAAATTCCCCAATTAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10957.35 Da        Isoelectric Point: 8.0314

>AT125057 WP_021179086.1 NZ_CP040182:807380-807667 [Serratia fonticola]
MESRIQFRIENETKLLAQKAAEAKGTTLSEACRRLAQQMADDQRAAEEHENWLKDKVDAAFARLHEGEAVYLTQRQAEER
MSDFKAKVRAKYATK

Download         Length: 288 bp

>AT125057 NZ_CP040182:807380-807667 [Serratia fonticola]
ATGGAAAGCCGTATCCAGTTTCGCATTGAAAATGAAACTAAACTGTTGGCACAGAAAGCTGCTGAAGCGAAAGGGACGAC
CTTAAGTGAAGCCTGTCGGCGTTTAGCGCAACAAATGGCGGACGATCAACGTGCTGCTGAAGAACACGAAAACTGGTTGA
AAGATAAGGTTGATGCAGCCTTTGCCCGTTTGCATGAAGGAGAGGCTGTTTATCTTACCCAGCGGCAAGCTGAGGAGAGA
ATGAGCGACTTTAAAGCCAAAGTCAGGGCGAAATACGCAACCAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBU2NJB3

References