Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 417145..417896 Replicon chromosome
Accession NZ_CP040182
Organism Serratia fonticola strain MS5

Toxin (Protein)


Gene name ataT Uniprot ID A0A8I0CSM1
Locus tag FD644_RS01870 Protein ID WP_059199146.1
Coordinates 417145..417627 (-) Length 161 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID A0A3G2FKC3
Locus tag FD644_RS01875 Protein ID WP_059199145.1
Coordinates 417618..417896 (-) Length 93 a.a.

Genomic Context

FD644_RS01845FD644_RS01850FD644_RS01855FD644_RS01860FD644_RS01880FD644_RS01885FD644_RS01890FD644_RS01905FD644_RS01865FD644_RS01870FD644_RS01875FD644_RS01895FD644_RS01900
Location: 413180..413758 (579 bp)
Type: Others
Protein ID: WP_071681669.1
Location: 413831..414406 (576 bp)
Type: Others
Protein ID: WP_021807716.1
Location: 414599..415843 (1245 bp)
Type: Others
Protein ID: WP_071681671.1
Location: 416096..416311 (216 bp)
Type: Others
Protein ID: WP_071681673.1
Location: 418131..419165 (1035 bp)
Type: Others
Protein ID: WP_071681677.1
Location: 419171..419398 (228 bp)
Type: Others
Protein ID: WP_071681679.1
Location: 419594..419830 (237 bp)
Type: Others
Protein ID: WP_021181593.1
Location: 422128..422526 (399 bp)
Type: Others
Protein ID: WP_071681685.1
Location: 416305..416997 (693 bp)
Type: Others
Protein ID: WP_071681675.1
Location: 417145..417627 (483 bp)
Type: Toxin
Protein ID: WP_059199146.1
Location: 417618..417896 (279 bp)
Type: Antitoxin
Protein ID: WP_059199145.1
Location: 420164..420637 (474 bp)
Type: Others
Protein ID: WP_071681681.1
Location: 420621..421451 (831 bp)
Type: Others
Protein ID: WP_071681683.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FD644_RS01845413180..413758+579WP_071681669.1tellurium resistance membrane protein TerD-
FD644_RS01850413831..414406+576WP_021807716.1TerD family protein-
FD644_RS01855414599..415843+1245WP_071681671.1VWA domain-containing protein-
FD644_RS01860416096..416311+216WP_071681673.1hypothetical protein-
FD644_RS01865416305..416997-693WP_071681675.1HAD-IB family hydrolase-
FD644_RS01870417145..417627-483WP_059199146.1GNAT family N-acetyltransferaseToxin
FD644_RS01875417618..417896-279WP_059199145.1DUF1778 domain-containing proteinAntitoxin
FD644_RS01880418131..419165+1035WP_071681677.1YeeE/YedE family protein-
FD644_RS01885419171..419398+228WP_071681679.1sulfurtransferase TusA family protein-
FD644_RS01890419594..419830+237WP_021181593.1DUF4282 domain-containing protein-
FD644_RS01895420164..420637-474WP_071681681.1hypothetical protein-
FD644_RS01900420621..421451-831WP_071681683.1winged helix-turn-helix domain-containing protein-
FD644_RS01905422128..422526+399WP_071681685.1helix-turn-helix domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--417145..42864911504


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(43-144)

Antitoxin

Vibrio phage ICP1, Orf50

(2-92)


Sequences

Toxin        


Download         Length: 161 a.a.        Molecular weight: 17698.56 Da        Isoelectric Point: 9.6140

>T125055 WP_059199146.1 NZ_CP040182:c417627-417145 [Serratia fonticola]
MGMKAPEPLSSGHNLADFCSSEPMLNEWLRKKALKNHSAGISRVYVICAEETHRVIGYYCLATGSVQRNTAPGAYRRNAP
ESLPVIVLGRLAIDQAYSGKGLGVALLKDAIFRTNNIAQQVGVRALIVHALNEEVRNFYIKFAFSPSPEHPLMLFYPIKL

Download         Length: 483 bp

>T125055 NZ_CP040182:c417627-417145 [Serratia fonticola]
ATGGGAATGAAAGCTCCCGAGCCCTTGTCATCCGGGCATAACCTCGCTGACTTTTGCAGTTCAGAGCCGATGCTTAATGA
GTGGCTGAGAAAGAAAGCGCTTAAAAATCATAGCGCAGGAATTTCCCGCGTTTATGTTATTTGCGCAGAGGAAACCCATA
GGGTCATTGGATACTATTGCCTAGCAACGGGTAGCGTTCAGAGGAATACCGCCCCCGGAGCTTACAGACGCAATGCGCCA
GAGTCACTTCCAGTTATCGTTCTTGGCAGACTTGCTATCGATCAGGCGTACTCAGGTAAGGGTCTGGGGGTCGCATTGTT
AAAAGACGCGATATTTCGGACAAATAATATTGCTCAACAAGTTGGCGTGAGAGCGTTAATTGTTCATGCATTGAATGAAG
AGGTGCGAAACTTCTACATCAAGTTCGCCTTCTCCCCCTCCCCTGAACACCCACTGATGCTGTTTTATCCAATAAAGCTT
TAG

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10641.12 Da        Isoelectric Point: 4.4247

>AT125055 WP_059199145.1 NZ_CP040182:c417896-417618 [Serratia fonticola]
MKPETREAPINIRAKASQRDLIDMAASLLSKSRTDFMLEVACREAQDILLDQRLFILDDEQYDAFLTELDAPITAERQAR
INDLMSRKSPWE

Download         Length: 279 bp

>AT125055 NZ_CP040182:c417896-417618 [Serratia fonticola]
ATGAAACCTGAAACTAGAGAAGCCCCGATCAATATTCGGGCAAAAGCGTCTCAACGCGACCTGATCGATATGGCTGCAAG
TCTCTTGTCGAAATCGCGTACCGATTTCATGCTTGAAGTGGCTTGCCGCGAGGCGCAGGACATCCTACTGGACCAGCGTT
TGTTTATCTTAGACGACGAACAGTATGATGCGTTTCTGACCGAACTGGATGCGCCTATCACCGCTGAACGCCAGGCCCGT
ATTAACGACCTGATGAGCCGCAAATCGCCATGGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A3G2FKC3

References