Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeV-yfjZ/CbtA-CbeA
Location 362454..363228 Replicon chromosome
Accession NZ_CP040182
Organism Serratia fonticola strain MS5

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag FD644_RS01625 Protein ID WP_071682741.1
Coordinates 362454..362789 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag FD644_RS01630 Protein ID WP_071682742.1
Coordinates 362866..363228 (+) Length 121 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FD644_RS01580 358111..358743 + 633 WP_071682734.1 EcsC family protein -
FD644_RS01585 358877..359233 + 357 WP_071682735.1 hypothetical protein -
FD644_RS01590 359252..359710 + 459 WP_071682736.1 hypothetical protein -
FD644_RS01595 359770..360075 + 306 WP_081367074.1 hypothetical protein -
FD644_RS01600 360139..360450 + 312 WP_071682737.1 hypothetical protein -
FD644_RS01605 360701..361141 + 441 WP_137751230.1 antirestriction protein -
FD644_RS01610 361197..361577 + 381 WP_071682738.1 hypothetical protein -
FD644_RS01615 361574..361894 + 321 WP_071682739.1 hypothetical protein -
FD644_RS01620 361958..362440 + 483 WP_071682740.1 hypothetical protein -
FD644_RS01625 362454..362789 + 336 WP_071682741.1 TA system toxin CbtA family protein Toxin
FD644_RS01630 362866..363228 + 363 WP_071682742.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
FD644_RS01635 363309..364170 + 862 Protein_312 DUF4942 domain-containing protein -
FD644_RS01640 364591..367032 + 2442 WP_071682743.1 SIR2 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 330743..371445 40702


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(8-104)

Antitoxin

Antitoxin CbeA

(14-112)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12620.45 Da        Isoelectric Point: 8.0503

>T125054 WP_071682741.1 NZ_CP040182:362454-362789 [Serratia fonticola]
MKAIDKIPRTTSNANQALAEYRQLLTWLLNHCYGLELNDTPYHNPHAIAQQIEYGMTVRETINEMVEKFDLVRIDRPGFS
LLAQDPTLSGGDMLRARSALGLRNPVNRRLA

Download         Length: 336 bp

>T125054 NZ_CP040182:362454-362789 [Serratia fonticola]
ATGAAGGCCATCGACAAAATACCCCGCACCACATCTAACGCCAATCAGGCGTTGGCCGAGTACCGGCAACTGCTTACCTG
GTTGCTGAACCACTGTTATGGATTAGAACTCAACGATACGCCGTATCACAACCCACACGCTATCGCTCAACAGATTGAGT
ACGGAATGACGGTACGGGAAACCATCAATGAGATGGTGGAGAAATTCGACCTGGTACGCATTGACCGCCCCGGTTTCAGC
CTGCTGGCACAGGACCCGACGCTGAGTGGTGGGGATATGCTACGCGCCCGCAGTGCGCTAGGGCTACGAAACCCCGTCAA
TCGTCGCCTCGCCTGA

Antitoxin


Download         Length: 121 a.a.        Molecular weight: 13153.20 Da        Isoelectric Point: 6.8503

>AT125054 WP_071682742.1 NZ_CP040182:362866-363228 [Serratia fonticola]
MKNLEPDIPPTAPVWGLQCAITPRLGARLVQQGRHLHFLADRAGLIGTFTPEALKALDVAFPVLIEQLENYLRSGELDPR
RQNCITVHHAGFICGADTLGSFGYVYIAVYQAARPTVAEL

Download         Length: 363 bp

>AT125054 NZ_CP040182:362866-363228 [Serratia fonticola]
ATGAAAAATCTCGAACCTGATATCCCACCCACGGCTCCGGTCTGGGGTCTGCAATGTGCTATTACGCCACGTCTGGGGGC
CAGACTGGTACAACAGGGTCGGCACCTACATTTTCTGGCTGATCGCGCTGGTTTGATCGGCACGTTCACACCCGAAGCCC
TCAAGGCTCTCGATGTGGCTTTTCCGGTGTTGATTGAACAATTGGAGAACTATCTGCGCTCCGGTGAGCTCGATCCACGT
CGTCAGAATTGTATCACTGTTCATCATGCAGGTTTTATCTGTGGAGCCGATACGCTGGGCAGTTTTGGTTATGTGTATAT
CGCGGTCTATCAAGCGGCGCGGCCAACTGTTGCAGAACTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References