124999

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3026267..3026412 Replicon chromosome
Accession NZ_CP040122
Organism Klebsiella pneumoniae strain LSH-KPN148

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3026274..3026376 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3026267..3026412 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FDY04_RS14825 3021799..3023232 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
FDY04_RS14830 3023348..3023587 + 240 WP_002911393.1 YebV family protein -
FDY04_RS14835 3023685..3023876 + 192 WP_002911395.1 YebW family protein -
FDY04_RS14840 3023873..3024526 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
FDY04_RS14845 3024683..3025651 + 969 WP_004151446.1 VirK/YbjX family protein -
FDY04_RS14850 3025756..3025899 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3026267..3026412 + 146 - - Antitoxin
- 3026274..3026376 - 103 - - Toxin
FDY04_RS14855 3026535..3026873 - 339 WP_002911404.1 YebY family protein -
FDY04_RS14860 3026890..3027759 - 870 WP_062955019.1 copper homeostasis membrane protein CopD -
FDY04_RS14865 3027763..3028137 - 375 WP_004151448.1 CopC domain-containing protein YobA -
FDY04_RS14870 3028250..3028480 + 231 WP_002911406.1 DNA polymerase III subunit theta -
FDY04_RS14875 3028559..3029218 + 660 WP_002911407.1 exodeoxyribonuclease X -
FDY04_RS14880 3029222..3031282 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T124999 NZ_CP040122:c3026376-3026274 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT124999 NZ_CP040122:3026267-3026412 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References