Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-HTH
Location 587067..587671 Replicon plasmid unnamed1
Accession NZ_CP040096
Organism Pantoea sp. SO10

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FCN45_RS22230 Protein ID WP_137387305.1
Coordinates 587067..587219 (+) Length 51 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FCN45_RS22240 Protein ID WP_137387307.1
Coordinates 587345..587671 (+) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FCN45_RS22190 582787..583473 - 687 WP_137387446.1 hypothetical protein -
FCN45_RS22195 583652..584005 + 354 WP_101761588.1 DUF1428 domain-containing protein -
FCN45_RS22200 584118..584513 - 396 WP_137387301.1 VOC family protein -
FCN45_RS22205 584694..585557 + 864 WP_137387302.1 substrate-binding domain-containing protein -
FCN45_RS22210 585584..585934 + 351 WP_137387303.1 DUF3147 family protein -
FCN45_RS22220 586133..586423 - 291 WP_101761585.1 hypothetical protein -
FCN45_RS22225 586541..586792 - 252 WP_137387304.1 two-component-system connector protein YcgZ -
FCN45_RS22230 587067..587219 + 153 WP_137387305.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FCN45_RS22240 587345..587671 + 327 WP_137387307.1 helix-turn-helix domain-containing protein Antitoxin
FCN45_RS22245 587774..588607 - 834 WP_137387308.1 oxidoreductase -
FCN45_RS22250 588720..589655 + 936 WP_137387309.1 AraC family transcriptional regulator -
FCN45_RS22255 589710..590912 + 1203 WP_137387310.1 FAD-dependent oxidoreductase -
FCN45_RS22260 591072..591959 - 888 WP_137387311.1 aromatic amino acid DMT transporter YddG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - hcp/tssD 1..744154 744154


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(1-49)

Antitoxin

Cro/C1-type helix-turn-helix domain

(54-95)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5467.45 Da        Isoelectric Point: 9.9277

>T124944 WP_137387305.1 NZ_CP040096:587067-587219 [Pantoea sp. SO10]
MAIYVLKPFDRNTKGDAIDSAKLCKAALEVMAGIYEASFGGGVYKKRIQK

Download         Length: 153 bp

>T124944 NZ_CP040096:587067-587219 [Pantoea sp. SO10]
ATGGCAATTTATGTCTTAAAGCCATTCGATAGAAACACCAAAGGTGACGCTATCGATAGTGCAAAATTATGCAAAGCGGC
GCTGGAAGTCATGGCAGGGATTTATGAAGCCAGTTTCGGCGGGGGAGTTTACAAGAAGCGCATTCAAAAGTAG

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12427.46 Da        Isoelectric Point: 8.5614

>AT124944 WP_137387307.1 NZ_CP040096:587345-587671 [Pantoea sp. SO10]
MVNHLKDLQEIARDFNEIGVVTDELKEKIDSRVRLRELRASLPVLHMMSGDEINQLRQRYNLSQAMLAAYVGMSVGTVVK
WEREEKKPNGAALRLLNLIERKGLEVLQ

Download         Length: 327 bp

>AT124944 NZ_CP040096:587345-587671 [Pantoea sp. SO10]
ATGGTTAATCATCTGAAAGATCTACAAGAGATCGCCAGGGATTTTAATGAAATTGGTGTGGTCACCGATGAGCTAAAAGA
AAAAATTGATTCTCGTGTGAGATTGCGTGAATTGCGCGCTTCGCTACCTGTCCTGCACATGATGTCGGGAGATGAAATAA
ATCAGTTACGTCAACGTTATAATCTGAGCCAGGCGATGCTGGCCGCCTACGTCGGCATGTCAGTGGGGACGGTAGTGAAG
TGGGAACGAGAAGAGAAAAAACCTAACGGAGCAGCACTGCGATTGCTCAATCTTATCGAGCGAAAGGGGTTGGAAGTGCT
GCAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References