Detailed information of TA system TA124942

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PP_4151-4152/excise(antitoxin)
• Location: 416927..417963
• Replicon: plasmid unnamed1
• Accession: NZ_CP040096
• Organism: Pantoea sp. SO10

Toxin (Protein)

• Gene name: PP_4152
• Uniprot ID: -
• Locus tag: FCN45_RS21445
• Protein ID: WP_137387195.1
• Coordinates: 417388..417963 (+)
• Length: 192 a.a.

Antitoxin (Protein)

• Gene name: PP_4151
• Uniprot ID: -
• Locus tag: FCN45_RS21440
• Protein ID: WP_137387194.1
• Coordinates: 416927..417388 (+)
• Length: 154 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FCN45_RS21425	413307..414473	-	1167	WP_101761114.1	lycopene beta-cyclase CrtY	-
FCN45_RS21430	414473..415750	-	1278	WP_137387193.1	glycosyltransferase	-
FCN45_RS21435	415765..416670	-	906	WP_101761112.1	polyprenyl synthetase family protein	-
FCN45_RS21440	416927..417388	+	462	WP_137387194.1	helix-turn-helix domain-containing protein	Antitoxin
FCN45_RS21445	417388..417963	+	576	WP_137387195.1	PIN domain-containing protein	Toxin
FCN45_RS21450	418105..419046	+	942	WP_137387196.1	2-hydroxyacid dehydrogenase	-
FCN45_RS21455	419165..420346	+	1182	WP_137387197.1	FAD-binding oxidoreductase	-
FCN45_RS21460	420387..421757	-	1371	WP_137387439.1	trehalose-6-phosphate synthase	-
FCN45_RS21465	422257..422748	+	492	WP_137387198.1	GNAT family N-acetyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	hcp/tssD	1..744154	744154

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (8-115)

Antitoxin

• Helix-turn-helix domain, group 17 (84-132)

Sequences

Toxin

Protein

• Length: 192 a.a.
• Molecular weight: 21472.05 Da
• Isoelectric Point: 5.6952

>T124942 WP_137387195.1 NZ_CP040096:417388-417963 [Pantoea sp. SO10]
MNHSPYAVVLDACVLYPSILRDVLLRLGLTGLYQPKWTATIQDEWKRNLRTNRPDIAEDQLARTQTLMNKALPDAMVSGF
EPLISGIALPDSNDCHVVAAAIRCKAEVIVTMNLKDFPRNLMAEFEIEALHPDEFIMDLFDLNQALVLKAVNAQRASFRQ
PAMGVTVYLDSLLRQGLPMTVSALDKFRFLI

Nucleotide

• Length: 576 bp

>T124942 NZ_CP040096:417388-417963 [Pantoea sp. SO10]
ATGAACCATTCACCCTATGCCGTGGTACTGGATGCATGTGTGTTGTATCCATCCATACTGCGCGATGTACTGCTTCGCCT
CGGTCTGACGGGGCTCTACCAGCCAAAATGGACTGCCACCATTCAGGATGAATGGAAGCGTAATTTACGCACTAACAGAC
CAGATATTGCTGAAGATCAGTTGGCGCGCACGCAGACATTGATGAATAAAGCGCTTCCAGATGCAATGGTATCGGGATTT
GAACCGCTTATTTCTGGCATTGCATTACCTGATTCCAATGACTGCCATGTTGTCGCTGCCGCTATACGGTGTAAAGCTGA
AGTGATTGTCACAATGAATCTGAAGGATTTCCCGAGAAACCTCATGGCTGAATTCGAAATTGAAGCTCTTCATCCTGACG
AATTCATCATGGATCTGTTCGACTTAAATCAGGCGCTGGTTTTGAAGGCAGTGAATGCGCAACGCGCGAGTTTTAGACAA
CCAGCAATGGGCGTTACGGTTTATCTGGATTCGTTATTACGCCAGGGTTTACCGATGACAGTAAGCGCATTAGATAAGTT
TCGTTTTCTCATTTAG

Antitoxin

Protein

• Length: 154 a.a.
• Molecular weight: 17075.39 Da
• Isoelectric Point: 6.3786

>AT124942 WP_137387194.1 NZ_CP040096:416927-417388 [Pantoea sp. SO10]
MKHSILDSLSLPAPKEIEAASRGQRELATYLSTKQETQKISIQDAHNETHQIELPTSALTLLMAVLGELAVGNAVQVVPV
HAELTTQEAANILNVSRPHLVKLLEQGQLPYHKTGRHRRVLFADLMQFKDKRAQDSNDAMQELADQGQDLNFY

Nucleotide

• Length: 462 bp

>AT124942 NZ_CP040096:416927-417388 [Pantoea sp. SO10]
ATGAAACACTCAATTCTGGATAGCTTGAGCCTTCCGGCTCCGAAGGAGATTGAGGCCGCTTCGCGCGGGCAGAGGGAGCT
CGCAACTTATCTATCCACCAAGCAGGAAACGCAAAAAATATCGATTCAGGATGCGCACAACGAAACGCATCAGATTGAGC
TGCCAACGTCTGCCCTGACACTACTCATGGCTGTTTTGGGCGAGTTGGCGGTGGGAAATGCGGTTCAGGTTGTGCCTGTA
CACGCTGAATTAACTACGCAGGAAGCGGCAAATATTTTAAACGTTTCACGCCCACATTTGGTGAAACTGTTAGAGCAAGG
TCAGCTTCCGTACCATAAAACAGGTCGCCATCGTCGCGTGCTTTTTGCGGATCTTATGCAGTTTAAAGACAAGCGTGCGC
AAGATAGCAATGATGCAATGCAGGAATTGGCAGACCAGGGACAGGATCTCAATTTCTACTGA