Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 409696..410246 Replicon plasmid unnamed1
Accession NZ_CP040096
Organism Pantoea sp. SO10

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag FCN45_RS21400 Protein ID WP_137387189.1
Coordinates 409696..410004 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag FCN45_RS21405 Protein ID WP_137387190.1
Coordinates 410007..410246 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FCN45_RS21380 405812..406990 + 1179 WP_137387187.1 Gfo/Idh/MocA family oxidoreductase -
FCN45_RS21385 406999..407940 + 942 WP_101761122.1 sugar phosphate isomerase/epimerase -
FCN45_RS21390 408037..408381 + 345 WP_137387188.1 ArsR family transcriptional regulator -
FCN45_RS21395 408374..409564 - 1191 WP_101761120.1 MFS transporter -
FCN45_RS21400 409696..410004 - 309 WP_137387189.1 CcdB family protein Toxin
FCN45_RS21405 410007..410246 - 240 WP_137387190.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
FCN45_RS21410 410431..410964 + 534 WP_101761117.1 sterol desaturase family protein -
FCN45_RS21415 410903..411832 - 930 WP_137387191.1 phytoene/squalene synthase family protein -
FCN45_RS21420 411829..413310 - 1482 WP_137387192.1 phytoene desaturase -
FCN45_RS21425 413307..414473 - 1167 WP_101761114.1 lycopene beta-cyclase CrtY -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - hcp/tssD 1..744154 744154


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-101)

Antitoxin

Post-segregation antitoxin CcdA

(9-79)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 12035.88 Da        Isoelectric Point: 5.8576

>T124941 WP_137387189.1 NZ_CP040096:c410004-409696 [Pantoea sp. SO10]
MQYFIYRNTNRNSEYPYLVDVQSEIIGELASRIVIPLYPLNQFKKKQVERLNPVIKVEGEEFLVMTHEMASVRVSLLGDQ
VMDARVYRQRIKDSVDFVFDGF

Download         Length: 309 bp

>T124941 NZ_CP040096:c410004-409696 [Pantoea sp. SO10]
ATGCAATATTTTATTTATCGCAATACCAATAGGAACAGCGAGTACCCTTATCTGGTAGACGTTCAAAGTGAGATTATCGG
CGAACTGGCGTCACGAATCGTTATCCCGCTCTACCCTCTAAACCAGTTTAAAAAAAAGCAAGTTGAACGACTTAATCCGG
TAATCAAGGTTGAAGGCGAGGAATTTCTGGTCATGACTCACGAAATGGCCAGTGTGCGCGTGTCGCTTCTAGGCGATCAG
GTGATGGATGCACGTGTGTATCGCCAGCGGATTAAAGACTCGGTTGATTTTGTCTTTGATGGGTTTTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9055.19 Da        Isoelectric Point: 5.7219

>AT124941 WP_137387190.1 NZ_CP040096:c410246-410007 [Pantoea sp. SO10]
MPSTAVRQKKTVSVTLEPALLEQAREAGLNLSAILSKALHYEIRTTEAERWKRENSEGLQELNRITEEHGLLSDEYRTF

Download         Length: 240 bp

>AT124941 NZ_CP040096:c410246-410007 [Pantoea sp. SO10]
ATGCCTTCTACAGCCGTAAGACAAAAAAAAACTGTCAGCGTGACACTTGAACCTGCATTACTCGAGCAGGCTAGAGAAGC
AGGGCTCAATTTATCCGCCATCCTATCTAAAGCTTTACATTATGAAATTCGCACAACCGAAGCGGAAAGATGGAAGCGTG
AAAACAGTGAAGGTTTGCAGGAACTCAATCGCATAACCGAAGAACACGGTTTATTGTCGGATGAATACAGGACGTTTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References