Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yafW-ykfI/CbtA-CbeA
Location 1151905..1152558 Replicon chromosome
Accession NZ_CP040095
Organism Pantoea sp. SO10

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag FCN45_RS05255 Protein ID WP_137385325.1
Coordinates 1152229..1152558 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name yafW Uniprot ID -
Locus tag FCN45_RS05250 Protein ID WP_137385324.1
Coordinates 1151905..1152207 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FCN45_RS05235 1147851..1150250 - 2400 WP_137385322.1 type VI secretion system tip protein VgrG -
FCN45_RS05240 1150390..1151097 - 708 WP_137385323.1 type VI secretion system protein TssL, short form -
FCN45_RS05245 1151470..1151880 + 411 Protein_1008 hypothetical protein -
FCN45_RS05250 1151905..1152207 + 303 WP_137385324.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
FCN45_RS05255 1152229..1152558 + 330 WP_137385325.1 TA system toxin CbtA family protein Toxin
FCN45_RS05260 1152673..1153506 + 834 WP_137385326.1 DUF4942 domain-containing protein -
FCN45_RS05265 1153617..1154864 + 1248 WP_137385327.1 PD-(D/E)XK nuclease family protein -
FCN45_RS05270 1155106..1155438 - 333 Protein_1013 tyrosine-type recombinase/integrase -
FCN45_RS05275 1155657..1156376 + 720 WP_137385328.1 Rha family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1137455..1156376 18921


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(8-107)

Antitoxin

Antitoxin CbeA

(2-98)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12152.99 Da        Isoelectric Point: 5.0473

>T124933 WP_137385325.1 NZ_CP040095:1152229-1152558 [Pantoea sp. SO10]
MPTSAIHPRRAASCCLSPVVHWRTLLVYLLEKHFGMDLNDTPFCSELVILQHIEAGVTLADAINFLVEKYDLVRIDTLGD
TYSEPEIFLTAADILKASHATGLTQRNLD

Download         Length: 330 bp

>T124933 NZ_CP040095:1152229-1152558 [Pantoea sp. SO10]
ATGCCAACCTCAGCAATTCATCCGAGGCGGGCGGCATCGTGCTGCTTGTCACCTGTAGTGCACTGGCGAACATTACTTGT
GTACCTGCTGGAAAAGCATTTCGGAATGGATTTAAACGATACGCCATTTTGCAGTGAGTTAGTCATCCTGCAACACATCG
AAGCGGGTGTTACCCTGGCCGACGCCATCAATTTCCTGGTAGAAAAATATGACCTGGTGCGCATCGATACCCTTGGTGAT
ACCTATTCAGAGCCAGAAATCTTCCTGACCGCCGCCGACATACTGAAGGCAAGTCACGCTACCGGATTAACGCAGCGCAA
TCTCGATTAA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11303.84 Da        Isoelectric Point: 6.6321

>AT124933 WP_137385324.1 NZ_CP040095:1151905-1152207 [Pantoea sp. SO10]
MGLKRNIIPRFGARLVQEGNRLHFLSDRAGITGEFSEAQIERINQSFPPMVGMLEHLLTTGELNPYQQHCVTIYHNNLTC
EADTLGSQGYVYVSIYPTPH

Download         Length: 303 bp

>AT124933 NZ_CP040095:1151905-1152207 [Pantoea sp. SO10]
ATGGGGTTGAAACGTAATATTATTCCGCGCTTCGGTGCCCGACTGGTGCAGGAAGGCAACCGGCTGCACTTCCTGTCTGA
CCGGGCCGGAATAACCGGTGAATTTAGCGAAGCGCAAATCGAGCGTATCAATCAGTCATTCCCGCCAATGGTTGGCATGC
TTGAACATCTACTGACCACAGGCGAACTTAATCCGTACCAGCAGCATTGTGTCACGATTTATCACAATAACCTGACCTGC
GAAGCCGACACGCTCGGTTCGCAGGGCTACGTCTATGTTTCGATTTACCCGACACCTCACTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References