Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 6612123..6612682 Replicon chromosome
Accession NZ_CP040094
Organism Nostoc sp. TCL240-02

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FBB35_RS28220 Protein ID WP_174712393.1
Coordinates 6612123..6612461 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FBB35_RS28225 Protein ID WP_174712394.1
Coordinates 6612458..6612682 (-) Length 75 a.a.

Genomic Context

FBB35_RS28205FBB35_RS28210FBB35_RS28215FBB35_RS28240FBB35_RS28190FBB35_RS28195FBB35_RS28200FBB35_RS28220FBB35_RS28225FBB35_RS28230FBB35_RS28235FBB35_RS28245FBB35_RS28250FBB35_RS28255
Location: 6609515..6610417 (903 bp)
Type: Others
Protein ID: WP_174712390.1
Location: 6610490..6611347 (858 bp)
Type: Others
Protein ID: WP_174712391.1
Location: 6611469..6612041 (573 bp)
Type: Others
Protein ID: WP_174712392.1
Location: 6614681..6615010 (330 bp)
Type: Others
Protein ID: WP_114081874.1
Location: 6607431..6608261 (831 bp)
Type: Others
Protein ID: WP_174712388.1
Location: 6608579..6608782 (204 bp)
Type: Others
Protein ID: WP_094330501.1
Location: 6608793..6609356 (564 bp)
Type: Others
Protein ID: WP_174712389.1
Location: 6612123..6612461 (339 bp)
Type: Toxin
Protein ID: WP_174712393.1
Location: 6612458..6612682 (225 bp)
Type: Antitoxin
Protein ID: WP_174712394.1
Location: 6612892..6613836 (945 bp)
Type: Others
Protein ID: WP_174712395.1
Location: 6614003..6614578 (576 bp)
Type: Others
Protein ID: WP_174712396.1
Location: 6615172..6615474 (303 bp)
Type: Others
Protein ID: WP_012410383.1
Location: 6615551..6616240 (690 bp)
Type: Others
Protein ID: WP_174712397.1
Location: 6616216..6617316 (1101 bp)
Type: Others
Protein ID: WP_174712398.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FBB35_RS281906607431..6608261-831WP_174712388.1PD-(D/E)XK nuclease family protein-
FBB35_RS281956608579..6608782-204WP_094330501.1hypothetical protein-
FBB35_RS282006608793..6609356-564WP_174712389.1peptide deformylase-
FBB35_RS282056609515..6610417+903WP_174712390.1ABC transporter permease-
FBB35_RS282106610490..6611347+858WP_174712391.1DUF3598 family protein-
FBB35_RS282156611469..6612041+573WP_174712392.1Uma2 family endonuclease-
FBB35_RS282206612123..6612461-339WP_174712393.1DUF5615 family PIN-like proteinToxin
FBB35_RS282256612458..6612682-225WP_174712394.1DUF433 domain-containing proteinAntitoxin
FBB35_RS282306612892..6613836-945WP_174712395.1toll/interleukin-1 receptor domain-containing protein-
FBB35_RS282356614003..6614578-576WP_174712396.1leucyl/phenylalanyl-tRNA--protein transferase-
FBB35_RS282406614681..6615010+330WP_114081874.1hypothetical protein-
FBB35_RS282456615172..6615474-303WP_012410383.130S ribosomal protein S14-
FBB35_RS282506615551..6616240-690WP_174712397.1endonuclease III-
FBB35_RS282556616216..6617316-1101WP_174712398.1RIP metalloprotease RseP-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-78)

Antitoxin

Protein of unknown function DUF433

(8-63)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12470.26 Da        Isoelectric Point: 4.3216

>T124929 WP_174712393.1 NZ_CP040094:c6612461-6612123 [Nostoc sp. TCL240-02]
MTIWVDAHLSPAIATWITITFGITALALRDVGLRDAEDPEIFEAARAREVIFMTKDSDFADLVDRFGSPPQVIWLTCGNT
SNARLKEILNSTLPEALELLRSGEALVEIRRD

Download         Length: 339 bp

>T124929 NZ_CP040094:c6612461-6612123 [Nostoc sp. TCL240-02]
ATGACAATCTGGGTAGATGCACATCTGTCACCTGCAATTGCAACTTGGATCACCATCACATTCGGCATAACGGCATTAGC
TTTGCGTGATGTTGGGCTGAGAGATGCCGAAGATCCTGAGATTTTTGAGGCAGCGAGGGCTAGAGAAGTTATTTTTATGA
CCAAAGACAGTGACTTTGCTGACTTGGTTGATCGTTTTGGAAGTCCACCACAAGTTATCTGGTTGACGTGTGGTAATACG
TCAAATGCACGATTGAAAGAGATTCTGAATTCAACATTGCCAGAAGCATTAGAGCTTTTGCGATCTGGTGAAGCGTTAGT
CGAAATCAGAAGGGATTAA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8062.44 Da        Isoelectric Point: 5.7582

>AT124929 WP_174712394.1 NZ_CP040094:c6612682-6612458 [Nostoc sp. TCL240-02]
MSDLLGRITVNPKQCGGRPCIRGMRIRVSDVLDLFAAGLSAEQILEEMPDLEADDLKAALVYASRKLNHPVLVA

Download         Length: 225 bp

>AT124929 NZ_CP040094:c6612682-6612458 [Nostoc sp. TCL240-02]
ATGTCAGACTTACTTGGAAGAATTACAGTTAATCCTAAACAATGTGGTGGTCGTCCCTGTATCAGAGGCATGAGAATTCG
GGTATCAGACGTACTCGACTTGTTTGCGGCAGGACTGAGTGCCGAACAAATCCTAGAAGAAATGCCCGATCTGGAAGCGG
ATGATCTTAAAGCAGCACTTGTGTACGCTTCACGTAAGCTCAATCATCCCGTTTTGGTTGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References