Detailed information of TA system TA124891

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 83096..83749
• Replicon: chromosome
• Accession: NZ_CP040080
• Organism: Acinetobacter baumannii strain SP304

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: FDM99_RS00430
• Protein ID: WP_137344701.1
• Coordinates: 83096..83485 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: FDM99_RS00435
• Protein ID: WP_001288210.1
• Coordinates: 83492..83749 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FDM99_RS00415	78214..80409	-	2196	WP_137344700.1	TRAP transporter large permease subunit	-
FDM99_RS00420	80597..81163	-	567	WP_000651536.1	rhombosortase	-
FDM99_RS00425	81241..82326	-	1086	WP_000049106.1	hypothetical protein	-
FDM99_RS00430	83096..83485	-	390	WP_137344701.1	hypothetical protein	Toxin
FDM99_RS00435	83492..83749	-	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
FDM99_RS00440	83937..85109	+	1173	WP_001190546.1	acyl-CoA dehydrogenase family protein	-
FDM99_RS00445	85158..86648	-	1491	WP_000415132.1	NAD(P)/FAD-dependent oxidoreductase	-
FDM99_RS00450	86830..87207	-	378	WP_001216380.1	50S ribosomal protein L17	-
FDM99_RS00455	87226..88233	-	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15603.85 Da
• Isoelectric Point: 10.3890

>T124891 WP_137344701.1 NZ_CP040080:c83485-83096 [Acinetobacter baumannii]
MINHSNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQISLAEWKKLKILEKLY

Nucleotide

• Length: 390 bp

>T124891 NZ_CP040080:c83485-83096 [Acinetobacter baumannii]
TTGATCAACCATTCGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATCACTCACAGAACACCATT
TCACGCGTCAAAATTTTAAAAATAATTGATTATCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATATCATTAGCAGAGTGGAAAAAGCTTAAAATTTTAGAAAAACTCTATTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT124891 WP_001288210.1 NZ_CP040080:c83749-83492 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT124891 NZ_CP040080:c83749-83492 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTATTTGCTGAGTTGGTAGAACAGGAAG
ATCCTGATTTACTCGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7