Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 1259821..1260416 Replicon chromosome
Accession NZ_CP040078
Organism Burkholderia sp. DHOD12

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag FAZ95_RS27730 Protein ID WP_137335671.1
Coordinates 1260066..1260416 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag FAZ95_RS27725 Protein ID WP_137335670.1
Coordinates 1259821..1260072 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FAZ95_RS27705 1255623..1256408 + 786 WP_137335667.1 enoyl-ACP reductase FabI -
FAZ95_RS27710 1256481..1256738 + 258 WP_137335668.1 RNA-binding protein -
FAZ95_RS27715 1256713..1257453 - 741 WP_137335669.1 response regulator -
FAZ95_RS27720 1257479..1259536 - 2058 WP_137337631.1 potassium-transporting ATPase subunit KdpB -
FAZ95_RS27725 1259821..1260072 + 252 WP_137335670.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
FAZ95_RS27730 1260066..1260416 + 351 WP_137335671.1 type II toxin-antitoxin system ChpB family toxin Toxin
FAZ95_RS27735 1260502..1261794 - 1293 WP_137335672.1 aspartate carbamoyltransferase -
FAZ95_RS27740 1262136..1262993 + 858 WP_137335673.1 4-hydroxy-tetrahydrodipicolinate synthase -
FAZ95_RS27745 1263050..1263796 - 747 WP_137335674.1 hypothetical protein -
FAZ95_RS27750 1263874..1264326 - 453 WP_137335675.1 rhodanese-like domain-containing protein -
FAZ95_RS27755 1264389..1265375 + 987 WP_137335676.1 transcriptional regulator FtrA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

Antitoxin PemI-like

(1-83)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12460.41 Da        Isoelectric Point: 8.9716

>T124887 WP_137335671.1 NZ_CP040078:1260066-1260416 [Burkholderia sp. DHOD12]
MVRRVKFERGDIVRVSLNPTIGREQQGDFRPALVLSPAAFNSLGVALVAPITQGGDFARFAGFAVPLSGSGTETQGVALV
NMVRMLDLDARGARKVERAPLEVVEDALARLQTIIE

Download         Length: 351 bp

>T124887 NZ_CP040078:1260066-1260416 [Burkholderia sp. DHOD12]
ATGGTGAGGCGGGTCAAGTTCGAGCGGGGCGATATCGTGCGCGTGAGCCTGAATCCAACTATCGGTCGTGAGCAGCAAGG
TGATTTTCGCCCAGCCCTCGTGCTCTCTCCGGCGGCGTTCAATTCCCTGGGCGTGGCGCTCGTCGCTCCGATCACGCAGG
GCGGGGACTTCGCCCGCTTTGCAGGCTTCGCGGTGCCGCTTTCCGGCTCGGGAACCGAGACGCAGGGCGTTGCCCTCGTG
AACATGGTGCGTATGCTCGATCTGGACGCGCGCGGCGCGCGCAAGGTTGAACGCGCGCCGCTCGAGGTGGTCGAGGACGC
GCTGGCGCGGCTTCAGACGATCATTGAGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 8976.34 Da        Isoelectric Point: 7.9812

>AT124887 WP_137335670.1 NZ_CP040078:1259821-1260072 [Burkholderia sp. DHOD12]
MELKIQKWGNSAAVRLPSVLLEQINASVGSSLSADVRPDGVLLSPARRKYSLDDLIAQCDKKASLPADMAAWGEVKPVGR
EAW

Download         Length: 252 bp

>AT124887 NZ_CP040078:1259821-1260072 [Burkholderia sp. DHOD12]
ATGGAACTCAAGATTCAAAAGTGGGGCAATAGTGCGGCAGTGCGTTTACCTAGCGTGCTGCTCGAACAGATCAACGCGTC
GGTCGGCAGCTCGTTGAGCGCAGACGTGCGCCCGGATGGCGTGTTGCTTTCTCCGGCTCGCCGCAAATATTCGCTCGACG
ATCTCATTGCCCAATGCGACAAGAAAGCGTCATTGCCGGCCGATATGGCGGCCTGGGGCGAGGTCAAACCGGTCGGGCGT
GAAGCATGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References