Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3358957..3359610 Replicon chromosome
Accession NZ_CP040050
Organism Acinetobacter baumannii strain VB16141

Toxin (Protein)


Gene name cptA Uniprot ID A0A246A3V9
Locus tag FDF20_RS16255 Protein ID WP_002054941.1
Coordinates 3358957..3359346 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag FDF20_RS16260 Protein ID WP_001288210.1
Coordinates 3359353..3359610 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FDF20_RS16240 3354076..3356271 - 2196 WP_001158905.1 TRAP transporter large permease subunit -
FDF20_RS16245 3356459..3357025 - 567 WP_000651536.1 rhombosortase -
FDF20_RS16250 3357103..3358188 - 1086 WP_000049106.1 hypothetical protein -
FDF20_RS16255 3358957..3359346 - 390 WP_002054941.1 hypothetical protein Toxin
FDF20_RS16260 3359353..3359610 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
FDF20_RS16265 3359798..3360970 + 1173 WP_045543714.1 acyl-CoA dehydrogenase family protein -
FDF20_RS16270 3361020..3362510 - 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
FDF20_RS16275 3362692..3363069 - 378 WP_001216380.1 50S ribosomal protein L17 -
FDF20_RS16280 3363088..3364095 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15616.87 Da        Isoelectric Point: 10.2790

>T124845 WP_002054941.1 NZ_CP040050:c3359346-3358957 [Acinetobacter baumannii]
MINHLNFKLKYSHFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKVIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

>T124845 NZ_CP040050:c3359346-3358957 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCATTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AATTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATCACTCACAGAACACCATT
TCTCGCGTCAAAATTTTAAAAGTAATTGATTATCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT124845 WP_001288210.1 NZ_CP040050:c3359610-3359353 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp

>AT124845 NZ_CP040050:c3359610-3359353 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ATCCTGATTTACTCGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A246A3V9

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References