Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2263594..2263739 | Replicon | chromosome |
| Accession | NZ_CP040038 | ||
| Organism | Klebsiella pneumoniae strain KPC160125 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2263601..2263703 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2263594..2263739 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FDK27_RS11635 | 2259125..2260558 | + | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| FDK27_RS11640 | 2260674..2260913 | + | 240 | WP_002911393.1 | YebV family protein | - |
| FDK27_RS11645 | 2261011..2261202 | + | 192 | WP_002911395.1 | YebW family protein | - |
| FDK27_RS11650 | 2261199..2261852 | - | 654 | WP_024622748.1 | protein-serine/threonine phosphatase | - |
| FDK27_RS11655 | 2262009..2262977 | + | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| FDK27_RS11660 | 2263082..2263225 | + | 144 | WP_038431282.1 | Ecr family regulatory small membrane protein | - |
| - | 2263594..2263739 | + | 146 | - | - | Antitoxin |
| - | 2263601..2263703 | - | 103 | - | - | Toxin |
| FDK27_RS11665 | 2263862..2264200 | - | 339 | WP_002911404.1 | YebY family protein | - |
| FDK27_RS11670 | 2264217..2265086 | - | 870 | WP_004175431.1 | copper homeostasis membrane protein CopD | - |
| FDK27_RS11675 | 2265090..2265464 | - | 375 | WP_039819395.1 | CopC domain-containing protein YobA | - |
| FDK27_RS11680 | 2265577..2265807 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| FDK27_RS11685 | 2265886..2266545 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| FDK27_RS11690 | 2266549..2268609 | - | 2061 | WP_004151449.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T124823 NZ_CP040038:c2263703-2263601 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT124823 NZ_CP040038:2263594-2263739 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
