Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2079832..2079977 | Replicon | chromosome |
| Accession | NZ_CP040028 | ||
| Organism | Klebsiella pneumoniae strain KPC160121 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2079868..2079970 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2079832..2079977 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FDK25_RS10395 | 2074962..2077022 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| FDK25_RS10400 | 2077026..2077685 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| FDK25_RS10405 | 2077764..2077994 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| FDK25_RS10410 | 2078107..2078481 | + | 375 | WP_039819395.1 | CopC domain-containing protein YobA | - |
| FDK25_RS10415 | 2078485..2079354 | + | 870 | WP_004175431.1 | copper homeostasis membrane protein CopD | - |
| FDK25_RS10420 | 2079371..2079709 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2079832..2079977 | - | 146 | - | - | Antitoxin |
| - | 2079868..2079970 | + | 103 | - | - | Toxin |
| FDK25_RS10425 | 2080346..2080489 | - | 144 | WP_038431282.1 | Ecr family regulatory small membrane protein | - |
| FDK25_RS10430 | 2080594..2081562 | - | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| FDK25_RS10435 | 2081719..2082372 | + | 654 | WP_024622748.1 | protein-serine/threonine phosphatase | - |
| FDK25_RS10440 | 2082369..2082560 | - | 192 | WP_002911395.1 | YebW family protein | - |
| FDK25_RS10445 | 2082658..2082897 | - | 240 | WP_002911393.1 | YebV family protein | - |
| FDK25_RS10450 | 2083013..2084446 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T124785 NZ_CP040028:2079868-2079970 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT124785 NZ_CP040028:c2079977-2079832 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
