Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2102908..2103053 | Replicon | chromosome |
| Accession | NZ_CP040023 | ||
| Organism | Klebsiella pneumoniae strain KPC160132 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2102944..2103046 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2102908..2103053 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FDK24_RS10575 | 2098038..2100098 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| FDK24_RS10580 | 2100102..2100761 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| FDK24_RS10585 | 2100840..2101070 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| FDK24_RS10590 | 2101183..2101557 | + | 375 | WP_039819395.1 | CopC domain-containing protein YobA | - |
| FDK24_RS10595 | 2101561..2102430 | + | 870 | WP_004175431.1 | copper homeostasis membrane protein CopD | - |
| FDK24_RS10600 | 2102447..2102785 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2102908..2103053 | - | 146 | - | - | Antitoxin |
| - | 2102944..2103046 | + | 103 | - | - | Toxin |
| FDK24_RS10605 | 2103422..2103565 | - | 144 | WP_038431282.1 | Ecr family regulatory small membrane protein | - |
| FDK24_RS10610 | 2103670..2104638 | - | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| FDK24_RS10615 | 2104795..2105448 | + | 654 | WP_024622748.1 | protein-serine/threonine phosphatase | - |
| FDK24_RS10620 | 2105445..2105636 | - | 192 | WP_002911395.1 | YebW family protein | - |
| FDK24_RS10625 | 2105734..2105973 | - | 240 | WP_002911393.1 | YebV family protein | - |
| FDK24_RS10630 | 2106089..2107522 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T124765 NZ_CP040023:2102944-2103046 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT124765 NZ_CP040023:c2103053-2102908 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
