Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 146134..146602 Replicon chromosome
Accession NZ_CP040022
Organism Salinivibrio kushneri strain AL184

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FCN78_RS13780 Protein ID WP_077651115.1
Coordinates 146393..146602 (+) Length 70 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FCN78_RS13775 Protein ID WP_198532969.1
Coordinates 146134..146400 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FCN78_RS13745 142633..143154 - 522 WP_077659251.1 GNAT family N-acetyltransferase -
FCN78_RS13760 144233..144469 - 237 WP_077659252.1 hypothetical protein -
FCN78_RS13765 144720..145196 - 477 WP_077659253.1 GNAT family N-acetyltransferase -
FCN78_RS13770 145352..145972 - 621 WP_077659254.1 LysE family translocator -
FCN78_RS13775 146134..146400 + 267 WP_198532969.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FCN78_RS13780 146393..146602 + 210 WP_077651115.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
FCN78_RS13785 146746..147525 - 780 WP_077659255.1 adenylate/guanylate cyclase -
FCN78_RS13790 147525..148088 - 564 WP_077659256.1 hypothetical protein -
FCN78_RS13795 148172..148738 - 567 WP_077659257.1 hypothetical protein -
FCN78_RS13800 148876..149385 - 510 WP_137317909.1 hypothetical protein -
FCN78_RS13805 149482..149949 - 468 WP_077659811.1 GNAT family N-acetyltransferase -
FCN78_RS13810 150039..150779 - 741 WP_077659810.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 144233..152820 8587


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-69)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-79)


Sequences

Toxin        


Download         Length: 70 a.a.        Molecular weight: 8011.34 Da        Isoelectric Point: 8.0487

>T124759 WP_077651115.1 NZ_CP040022:146393-146602 [Salinivibrio kushneri]
MLKLEYSSQFKKDFKKIAKLSIPDVVEVGHVIKQLQLGETLPEKYVDHSLSGNWQNYRDCHVKPDLVLI

Download         Length: 210 bp

>T124759 NZ_CP040022:146393-146602 [Salinivibrio kushneri]
ATGCTTAAACTCGAGTACTCAAGCCAATTTAAAAAGGACTTCAAGAAAATAGCAAAACTTTCGATTCCCGATGTAGTTGA
AGTCGGTCATGTCATTAAACAATTACAGCTCGGGGAAACACTACCGGAAAAATACGTTGATCATTCTTTGTCTGGAAACT
GGCAGAATTATCGAGATTGCCACGTAAAACCGGATTTAGTTTTGATTTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9485.72 Da        Isoelectric Point: 5.0361

>AT124759 WP_198532969.1 NZ_CP040022:146134-146400 [Salinivibrio kushneri]
MLSTRIDHDTKLAFTHVCENMGLSPSQAIKLFAKAVVNYGGIPFELKVKQPNAATASAISELESGKANTASNIEELFEEF
NIGKTDNA

Download         Length: 267 bp

>AT124759 NZ_CP040022:146134-146400 [Salinivibrio kushneri]
ATGCTGAGCACCCGAATTGACCACGACACCAAGTTAGCGTTTACTCACGTTTGCGAGAACATGGGACTTAGCCCCTCTCA
AGCAATAAAGCTTTTTGCCAAAGCGGTCGTTAATTACGGCGGCATACCCTTTGAGCTTAAAGTCAAGCAACCCAATGCAG
CAACAGCCTCAGCCATCTCCGAGCTCGAGTCCGGCAAGGCAAATACCGCCAGCAATATTGAAGAGCTATTCGAAGAATTC
AATATCGGTAAGACCGACAATGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References