Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 134741..135386 Replicon chromosome
Accession NZ_CP040022
Organism Salinivibrio kushneri strain AL184

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag FCN78_RS13710 Protein ID WP_069363033.1
Coordinates 134988..135386 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag FCN78_RS13705 Protein ID WP_077659247.1
Coordinates 134741..134974 (+) Length 78 a.a.

Genomic Context

FCN78_RS13685FCN78_RS13690FCN78_RS13705FCN78_RS13710FCN78_RS13695FCN78_RS13700FCN78_RS13715FCN78_RS13720FCN78_RS13725FCN78_RS13730
Location: 130132..132579 (2448 bp)
Type: Others
Protein ID: WP_077659244.1
Location: 132588..133559 (972 bp)
Type: Others
Protein ID: WP_106407183.1
Location: 134741..134974 (234 bp)
Type: Antitoxin
Protein ID: WP_077659247.1
Location: 134988..135386 (399 bp)
Type: Toxin
Protein ID: WP_069363033.1
Location: 133570..134004 (435 bp)
Type: Others
Protein ID: WP_077659245.1
Location: 133973..134485 (513 bp)
Type: Others
Protein ID: WP_077659246.1
Location: 135418..135699 (282 bp)
Type: Others
Protein ID: WP_021023566.1
Location: 135828..137276 (1449 bp)
Type: Others
Protein ID: WP_069363035.1
Location: 137288..138013 (726 bp)
Type: Others
Protein ID: WP_077659248.1
Location: 138010..139512 (1503 bp)
Type: Others
Protein ID: WP_077458389.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FCN78_RS13685130132..132579+2448WP_077659244.1DUF2309 domain-containing protein-
FCN78_RS13690132588..133559+972WP_106407183.1threonylcarbamoyl-AMP synthase-
FCN78_RS13695133570..134004-435WP_077659245.1PaaI family thioesterase-
FCN78_RS13700133973..134485-513WP_077659246.1NifB/NifX family molybdenum-iron cluster-binding protein-
FCN78_RS13705134741..134974+234WP_077659247.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
FCN78_RS13710134988..135386+399WP_069363033.1type II toxin-antitoxin system VapC family toxinToxin
FCN78_RS13715135418..135699-282WP_021023566.1DUF134 domain-containing protein-
FCN78_RS13720135828..137276-1449WP_069363035.1decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase-
FCN78_RS13725137288..138013-726WP_077659248.16-phosphogluconolactonase-
FCN78_RS13730138010..139512-1503WP_077458389.1glucose-6-phosphate dehydrogenase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

SpoVT-AbrB domain

(7-53)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14542.95 Da        Isoelectric Point: 8.7410

>T124758 WP_069363033.1 NZ_CP040022:134988-135386 [Salinivibrio kushneri]
MLDTCICSFIMREQPKAVLKKLHTVVGNQHRIVISAITYQEMQYGLLGKKASPKHAVLVDAFLQRIDEILPWDKAAVDAT
TAVKRNLMNKGTPIGGNDTAIAGHAIATGCVLVTNNTREFQRVEGLKLEDWA

Download         Length: 399 bp

>T124758 NZ_CP040022:134988-135386 [Salinivibrio kushneri]
ATGCTTGATACATGTATTTGTTCATTCATTATGAGAGAGCAACCCAAAGCGGTGTTGAAAAAGCTTCACACTGTTGTCGG
CAATCAACATCGCATTGTTATCTCAGCCATTACCTATCAAGAAATGCAATACGGGTTGTTAGGAAAAAAAGCATCACCAA
AACATGCCGTGCTTGTTGATGCTTTTCTTCAGCGAATCGATGAGATTTTACCTTGGGATAAAGCCGCCGTTGACGCGACA
ACTGCAGTTAAGCGCAACCTAATGAATAAAGGCACCCCTATTGGCGGAAACGACACCGCGATTGCCGGTCACGCCATTGC
GACTGGTTGTGTGCTAGTCACAAACAATACGAGGGAGTTTCAGCGTGTTGAAGGACTGAAACTTGAAGATTGGGCTTAA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8995.10 Da        Isoelectric Point: 4.8668

>AT124758 WP_077659247.1 NZ_CP040022:134741-134974 [Salinivibrio kushneri]
MRTISIFKNGKNQAVRLPKDFEFDGVNELEIHKEGDVITLRPARPSWLSFGELEKADSDFITHREELIKDEGRFNFD

Download         Length: 234 bp

>AT124758 NZ_CP040022:134741-134974 [Salinivibrio kushneri]
ATGAGAACAATATCCATTTTCAAAAATGGCAAGAACCAAGCGGTACGCTTGCCAAAGGATTTTGAGTTTGACGGTGTTAA
TGAGCTTGAAATTCATAAAGAGGGGGATGTCATCACCTTACGCCCAGCTCGACCAAGTTGGCTCTCATTTGGCGAGCTCG
AAAAGGCTGATAGTGATTTCATAACCCATCGCGAGGAACTGATCAAAGATGAGGGGCGGTTCAACTTTGACTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References