Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 855870..856437 Replicon chromosome
Accession NZ_CP040006
Organism Schaalia odontolytica strain XH001

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FBF35_RS03710 Protein ID WP_081493511.1
Coordinates 856138..856437 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FBF35_RS03705 Protein ID WP_034496870.1
Coordinates 855870..856148 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FBF35_RS03680 852201..853250 + 1050 WP_060566770.1 lipoate--protein ligase family protein -
FBF35_RS03685 853318..853938 - 621 WP_060566772.1 NAAT family transporter -
FBF35_RS03690 853986..854684 - 699 WP_060566774.1 YggS family pyridoxal phosphate-dependent enzyme -
FBF35_RS03695 854800..855189 + 390 WP_060566776.1 YccF domain-containing protein -
FBF35_RS03700 855209..855718 + 510 WP_060566778.1 Cys-tRNA(Pro) deacylase -
FBF35_RS03705 855870..856148 + 279 WP_034496870.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FBF35_RS03710 856138..856437 + 300 WP_081493511.1 type II toxin-antitoxin system YafQ family toxin Toxin
FBF35_RS03715 856475..857158 + 684 WP_034496886.1 Pr6Pr family membrane protein -
FBF35_RS03720 857212..857640 + 429 WP_007589492.1 VOC family protein -
FBF35_RS03725 857818..858381 + 564 WP_007589486.1 NAD(P)H-dependent oxidoreductase -
FBF35_RS03730 858458..859039 + 582 WP_131726644.1 TetR/AcrR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(12-99)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-68)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11429.31 Da        Isoelectric Point: 7.8873

>T124741 WP_081493511.1 NZ_CP040006:856138-856437 [Schaalia odontolytica]
MMSEPQRGQRALVMTSQFKKDLKRARKRGLPIKELEAVIDLILTGEVLPPQRRDHLLTGDYAGFRECHIRPDWLLIYLDE
PEICVVTAIRTGSHSDLFQ

Download         Length: 300 bp

>T124741 NZ_CP040006:856138-856437 [Schaalia odontolytica]
ATGATGAGTGAGCCTCAGCGGGGCCAGCGTGCCCTCGTGATGACCAGTCAATTCAAGAAGGATCTCAAAAGGGCCCGCAA
ACGAGGGCTCCCTATCAAGGAGCTCGAAGCGGTCATTGATCTCATTCTTACGGGCGAAGTGTTGCCTCCCCAGCGGAGGG
ATCATCTCTTGACCGGGGACTATGCGGGGTTCCGTGAATGTCATATTCGGCCGGATTGGCTGTTGATCTATCTGGATGAG
CCAGAGATCTGCGTTGTGACCGCAATTCGTACGGGTTCCCACTCGGACCTGTTTCAATAG

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10209.51 Da        Isoelectric Point: 4.6286

>AT124741 WP_034496870.1 NZ_CP040006:855870-856148 [Schaalia odontolytica]
MKTATLNMRVDPSVKEEAERVYAQFGMNLTDAVNVFLHKSIMEGGLPFDLRQPRFNAETELAMREARDIAAGRVAATRYA
SAAQAFADVDDE

Download         Length: 279 bp

>AT124741 NZ_CP040006:855870-856148 [Schaalia odontolytica]
ATGAAAACGGCGACGCTTAACATGCGCGTTGATCCAAGCGTGAAGGAAGAAGCTGAGAGGGTGTATGCCCAGTTCGGCAT
GAACCTCACCGACGCTGTGAATGTTTTCTTGCACAAGTCCATCATGGAGGGTGGCTTACCCTTTGACTTGCGCCAGCCCC
GCTTCAACGCTGAAACCGAGCTAGCTATGCGCGAGGCTCGCGACATCGCCGCAGGGCGTGTTGCCGCTACCCGTTACGCG
TCCGCGGCACAAGCGTTCGCGGATGTCGATGATGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References