Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2021184..2021328 | Replicon | chromosome |
| Accession | NZ_CP039957 | ||
| Organism | Klebsiella pneumoniae strain EAN23 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2021220..2021322 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2021184..2021328 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FC648_RS09945 | 2016314..2018374 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| FC648_RS09950 | 2018378..2019037 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| FC648_RS09955 | 2019116..2019346 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| FC648_RS09960 | 2019459..2019833 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| FC648_RS09965 | 2019837..2020706 | + | 870 | WP_020956678.1 | copper homeostasis membrane protein CopD | - |
| FC648_RS09970 | 2020723..2021061 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2021184..2021328 | - | 145 | - | - | Antitoxin |
| - | 2021220..2021322 | + | 103 | - | - | Toxin |
| FC648_RS09975 | 2021455..2021814 | - | 360 | WP_077253379.1 | tyrosine-type recombinase/integrase | - |
| FC648_RS09980 | 2021813..2022292 | + | 480 | WP_032419797.1 | lysis protein | - |
| FC648_RS09985 | 2023459..2024586 | + | 1128 | WP_064147220.1 | hypothetical protein | - |
| FC648_RS09990 | 2024836..2025264 | - | 429 | WP_032419788.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| FC648_RS09995 | 2025274..2025555 | - | 282 | WP_032419786.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T124673 NZ_CP039957:2021220-2021322 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 145 bp
>AT124673 NZ_CP039957:c2021328-2021184 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
