Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1984861..1985006 Replicon chromosome
Accession NZ_CP039954
Organism Klebsiella pneumoniae strain AR142_2b

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1984897..1984999 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1984861..1985006 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FC647_RS09515 1979991..1982051 + 2061 WP_004148850.1 oligopeptidase B -
FC647_RS09520 1982055..1982714 - 660 WP_032435029.1 exodeoxyribonuclease X -
FC647_RS09525 1982793..1983023 - 231 WP_002911406.1 DNA polymerase III subunit theta -
FC647_RS09530 1983136..1983510 + 375 WP_004151448.1 CopC domain-containing protein YobA -
FC647_RS09535 1983514..1984383 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
FC647_RS09540 1984400..1984738 + 339 WP_002911404.1 YebY family protein -
- 1984861..1985006 - 146 - - Antitoxin
- 1984897..1984999 + 103 - - Toxin
FC647_RS09545 1985374..1985517 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
FC647_RS09550 1985622..1986590 - 969 WP_004151446.1 VirK/YbjX family protein -
FC647_RS09555 1986747..1987400 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
FC647_RS09560 1987397..1987588 - 192 WP_002911395.1 YebW family protein -
FC647_RS09565 1987686..1987925 - 240 WP_002911393.1 YebV family protein -
FC647_RS09570 1988041..1989474 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T124651 NZ_CP039954:1984897-1984999 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT124651 NZ_CP039954:c1985006-1984861 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References